To investigate the clinical value of enhanced 128-detector CT scan in the preoperative staging of colorectal cancer.
Methods:
CT data of 30 patients with pathologically proved colorectal cancer were retrospectively reviewed (14 male and 16 female). Enhanced CT with multi-planner reconstruction was done to get CT staging. CT staging and pathological staging were compared.
Results:
In the 30 patients
22 (73%) tumors were correctly T-staged by CT. In T staging
the accuracy was 60% for T1+T2
78% for T3
and 100% for T4. The
sensitivity
specificity
positive predictive value and negative predictive value of diagnosing the invasion of plasma membrane were 80%
60%
80% and 60%
respectively. Nineteen (63%) tumors were correctly N-staged by CT. In N staging
the accuracy was 85% for N0
14% for N1
and 33% for N2
respectively. The sensitivity
specificity
positive predictive value and negative predictive value of diagnosing the lymph node metastasis were 40%
85%
57%
73%
respectively.
Conclusion:
Enhanced CT has some value in diagnosing T-staging
invasion of plasma membrane
N-staging and lymph node metastasis. The diagnostic accuracy of invasion of plasma membrane by enhanced 128-detector CT scan is comparatively high.