Imaging characteristics of typical medullary breast carcinoma and comparison with postoperative pathological features

CHU Zhaohui; LIANG Xiaohua; LIN Hao; HUANG Ruofan; ZHAN Qiong; JIANG Jingwei; ZHOU Xinli

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Imaging characteristics of typical medullary breast carcinoma and comparison with postoperative pathological features

更新时间：2025-12-31

- Imaging characteristics of typical medullary breast carcinoma and comparison with postoperative pathological features
- Vol. 24, Issue 3, Pages: 207-211(2015)
- 作者机构：
  
  1. 复旦大学附属华山医院肿瘤科,上海,200040
  2. 复旦大学上海医学院肿瘤学系和内科学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published Online：20 October 2015，
  
  Published：20 October 2015
- 稿件说明：
移动端阅览
初钊辉,梁晓华,林浩,等. 乳腺典型髓样癌影像学特征和术后病理对照分析[J]. 肿瘤影像学, 2015, 24(3): 207-211
DOI：

初钊辉,梁晓华,林浩,等. 乳腺典型髓样癌影像学特征和术后病理对照分析[J]. 肿瘤影像学, 2015, 24(3): 207-211 DOI：

摘要

目的：

探讨中国乳腺典型髓样癌(TMBC)的超声和乳腺X线摄影表现及病理学特征。

方法：

回顾性分析2004年1月2011年4月复旦大学附属华山医院收治的根治术前均行超声和乳腺X线摄影检查的80例TMBC患者，分析其影像学特征和术后病理结果及相关性。

结果：

患者术前乳腺X线摄影较超声更易发现肿块钙化点；两者联用诊断TMBC乳腺影像报告和数据系统（BI-RADS）分级最高均达4级以上。术前超声更易发现同侧腋淋巴结(ALN)肿大，但术后病理证实为淋巴结转移的仅占48.4%。超声和乳腺X线摄影均提示ALN肿大的患者中，87.5%经病理证实为淋巴结转移；原发灶位于外上象限的患者中，仅83.3%经病理证实转移；雌激素受体(ER)阴性患者中，仅85.7%经病理证实转移。

结论：

TMBC患者术前超声和乳腺X线摄影联合检查不易漏诊，两者均提示同侧ALN肿大时对淋巴结转移的预测意义较大，而对原发灶位于外上象限或ER阴性的患者需更加谨慎。

Abstract

Objective:

To investigate the ultrasonography and mammography characteristics and pathological features of typical medullary breast carcinoma (TMBC) in China.

Methods:

A retrospective analysis of imaging characteristics and pathological features of 80 TMBC patients during January 2004 and April 2011 was conducted. All patients accepted the examinations of ultrasonography and mammography before breast radical operation.

Results:

Mammography found more masses with calcification than ultrasonography. The highest grade of breast masses according to Breast Imaging Reporting and Data System (BI-RADS) classification scored above

grade 4 when ultrasonography was combined with mammography. Ultrasonography detected more enlarged ipsilateral axillary lymph nodes (ALNs) than mammography before operation

but only 48.4% patients with enlarged ALNs were confirmed to have metastasis by postoperative pathology. Up to 87.5% patients with enlarged ALNs found both by ultrasonography and mammography were confirmed to have metastasis. When the primary tumors were located in the upper outer quadrant

only 83.3% patients with enlarged ALNs were confirmed to have metastasis. When estrogen receptor (ER) was negative

only 85.7% patients with enlarged ALNs were confirmed to have metastasis.

Conclusion:

TMBC patients were not easily missed by combination of ultrasonography and mammography before operation. Enlarged ipsilateral ALNs shown by both ultrasonography and mammography indicate the high possibility of metastasis

which is needed to be cautious for patients with primary tumors located in the upper outer quadrant or with negative ER.

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