Diagnostic value of volume-based parameters by <sup>11</sup>C-methionine PET imaging in glioma patients

HUANG Zhemin; GE Jingjie; ZHANG Huiwei; REN Shuhua; GUAN Yihui

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Diagnostic value of volume-based parameters by ¹¹C-methionine PET imaging in glioma patients

更新时间：2025-12-15

- Diagnostic value of volume-based parameters by ¹¹C-methionine PET imaging in glioma patients
- Vol. 25, Issue 3, Pages: 252-256(2016)
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- Published Online：02 November 2016，
  
  Published：02 November 2016
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黄喆慜,葛璟洁,张慧玮,等. 基于¹¹C-蛋氨酸PET显像的肿瘤代谢体积参数在脑胶质瘤诊断中的应用价值研究[J]. 肿瘤影像学, 2016, 25(3): 252-256
DOI：

黄喆慜,葛璟洁,张慧玮,等. 基于¹¹C-蛋氨酸PET显像的肿瘤代谢体积参数在脑胶质瘤诊断中的应用价值研究[J]. 肿瘤影像学, 2016, 25(3): 252-256 DOI：

摘要

目的：

初步探索基于体积参数的蛋氨酸(methionine，MET)PET显像在胶质瘤诊断中的应用价值。

方法：

回顾性分析经术后病理证实的36例胶质瘤患者的MET PET图像并以此图像数据为基础计算相应的体积参数。

结果：

基于METPET图像的体积参数在不同世界卫生组织(World Health Organization，WHO)分级的胶质瘤之间存在显著差异，但当包括少突胶质细胞瘤时，WHO Ⅱ级与Ⅲ级胶质瘤之间体积参数差异不显著。

结论：

基于MET PET的代谢体积参数对胶质瘤诊断具有较好的应用价值，但实际应用时应注意考虑少突胶质细胞瘤等特殊摄取情况。

Abstract

Objective:

To explore the diagnostic value of volume-based parameters by

C-methionine (MET) PET imaging in glioma patients.

Methods:

A total of 36 patients who underwent surgical treatment and were confirmed of glioma were retrospectively analyzed. The volume-based parameters were calculated based on MET PET images.

Results:

The volumebased parameters showed significant differences among different grades of gliomas. When oligodendroglioma was considered

the difference between grade II and III was not significant.

Conclusion:

The volume-based parameters by MET PET are valuable in the diagnosis of glioma. The clinical application should be paid attention when certain type of tumor such as oligodendroglioma is

considered.

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Related Author

ZHANG Zhengwei

LU Xiuhong

LIN Huiqing

HUANG Li

LIN Li

TANG Yilin

HUA Tao

GUAN Yihui nbsp

Related Institution

Department of Radiotherapy, Huashan Hospital, Fudan University

Department of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University

Department of Neurosurgery, Shenzhen Longhua People&rsquo

Department of Neurosurgery, Hangzhou Cancer Hospital

Department of Neurology, Shenzhen Longhua People&rsquo

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Diagnostic value of volume-based parameters by 11C-methionine PET imaging in glioma patients

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摘要

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Diagnostic value of volume-based parameters by ¹¹C-methionine PET imaging in glioma patients