MRI and PET/CT imaging features of adult alveolar soft part sarcoma (ASPS).
Methods:
The clinical data
CT
MRI and PET/CT imaging features of ten patients with histopathologically proved ASPS from January 2012 to December 2016 were retrospectively reviewed.
Results:
The median age of the ten patients was 29 years (22-46 years). The median size of the lesions was 72 mm (29-260 mm). Seven lesions were in the extremities (4 cases in the thigh)
and 3 cases in the pelvic. Tumors were hyper-intensity on T1WI and heterogeneous hyper-intensity or mixed hypo-/hyper-intensity on T2WI. All lesions sh
owed marked heterogeneous enhancement and numerous large vessels on both contrast-enhanced T1WI and contrast-enhanced CT. All primary lesions and most of metastases were fluorodeoxyglucose (FDG)-avid on PET/CT. And metastases developed in 9 cases (9 cases in lungs
3 cases in lymph nodes
2 cases in bones
1 case in subcutaneous tissues and 1 case in brain).
Conclusion:
Adult ASPS predominantly develops in the extremities of young patients. Tumors show hyper-intensity on T1WI
and marked heterogeneous enhancement and numerous large vessels on both contrast-enhanced T1WI and contrast-enhanced CT. Pulmonary metastasis develops in the majority of ASPS patients.
Magnetic resonance imaging findings and clinicopathologic features of alveolar soft-part sarcoma
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Related Author
GAO Hui
HAN Lei
GUO Xiaoli
SHI Huixian
ZHANG Hongying
WU Jingtao
WANG Meng
LIU Zhou
Related Institution
Dalian Medical University
Clinical Medical College, Yangzhou University
Department of Radiology, Northern Jiangsu people&rsquo
Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College