Imaging characteristic analysis of triple-negative breast cancer

LIU Jiani; LUO Yahong

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Imaging characteristic analysis of triple-negative breast cancer

更新时间：2025-12-15

- Imaging characteristic analysis of triple-negative breast cancer
- Vol. 27, Issue 2, Pages: 75-81(2018)
- 作者机构：
- 作者简介：
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  CLC：
- Published Online：16 May 2018，
  
  Published：16 May 2018
- 稿件说明：
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刘佳妮,罗娅红. 三阴性乳腺癌的影像学特征分析[J]. 肿瘤影像学, 2018, 27(2): 75-81
DOI：

刘佳妮,罗娅红. 三阴性乳腺癌的影像学特征分析[J]. 肿瘤影像学, 2018, 27(2): 75-81 DOI：

摘要

目的：

探讨三阴性乳腺癌（triple-negative breast cancer，TNBC）的影像学特征，并与非三阴性乳腺癌（non-TNBC，NTNBC）进行比较。

方法：

回顾性分析辽宁省肿瘤医院经病理学及免疫组织化学证实的42例TNBC及504例NTNBC患者的乳腺X线及MRI表现，两组X线及MRI检查中病灶钙化、形态、边缘、T2信号、内部强化、时间-信号强度曲线（time-signal intensity curve，TIC）等比较采用

检验。

结果：

TNBC组病变最常见的X线表现为边缘清晰（12/25，48%）、圆形或类圆形（10/25，40%）、少钙化单纯肿块（17/28，61%）。TNBC组MRI常见表现为类圆形或结节状（22/27，82%）、边缘光滑（11/27，41%），T2WI序列呈高信号（5/27，18.5%）、环形强化（8/27，29.6%）、TIC呈速升速降型（20/32，63%）。TNBC组与NTNBC组乳腺X线肿块边缘及肿块钙化表现差异有统计学意义（

0.05）。两组MRI检查在肿块形态、边缘、强化方式、表观扩散系数（apparent diffusion coefficient，ADC）及TIC方面的差异有统计学意义（

0.05）。

结论：

TNBC的MRI检查中，如肿块边缘光滑，出现环形强化，TIC呈Ⅲ型，ADC值较高，结合乳腺X线检查所见，其对诊断TNBC有一定的参考价值。

Abstract

Objective:

To discuss the imaging characteristics of triple-negative breast cancer (TNBC) and to compare the results with characteristics of non-TNBC (NTNBC).

Methods:

Forty-two cases with TNBC and 504 cases with NTNBC confirmed by pathology and immunohistochemistry were retrospectively analyzed. Mammography and MRI were performed. The calcification

shape

edge

T2 signal

enhancement pattern and time-intensity curve (TIC) between the two groups were compared by c

hi-square test.

Results:

On mammography

TNBC usually presented with a round (10/25

40%) mass with less calcifications (17/28

61%)

and clear margins (12/25

48%). On MRI

the TNBC usually presented with a round (22/27

82%) mass with clear margins (11/27

41%)

high signal intensity on T2-weighted image (5/27

18.5%)

rim enhancement (8/27

29.6%) and type Ⅲ TIC (20/32

63%). There were statistically significant differences in calcification

edge on mammography between the two groups (

0.05). There were statistically significant differences in shape

edge

enhancement pattern

apparent diffusion coefficient (ADC) and TIC on MRI between the two groups (

0.05).

Conclusion:

On MRI

the TNBC usually presented with clear margins

rim enhancement

type Ⅲ TIC and a higher ADC. MRI combined with mammography findings has a certain value.

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