Contrast-enhanced ultrasound and MRI factors influencing therapeutic effects of high intensity focused ultrasound in treatment of hysteromyoma

JIN Lin; HU Baohua; FENG Lan; LI Ping; XU Rong; WANG Yingchun

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Contrast-enhanced ultrasound and MRI factors influencing therapeutic effects of high intensity focused ultrasound in treatment of hysteromyoma

更新时间：2025-12-15

- Contrast-enhanced ultrasound and MRI factors influencing therapeutic effects of high intensity focused ultrasound in treatment of hysteromyoma
- Vol. 27, Issue 2, Pages: 103-108(2018)
- 作者机构：
  
  1. 上海市嘉定区中心医院超声科,上海,201800
  2. 上海市嘉定区中心医院放射科,上海,201800
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published Online：16 May 2018，
  
  Published：16 May 2018
- 稿件说明：
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金琳,胡宝华,封岚,等. 高强度聚焦超声治疗子宫肌瘤效果的超声造影与MRI相关因素分析[J]. 肿瘤影像学, 2018, 27(2): 103-108
DOI：

金琳,胡宝华,封岚,等. 高强度聚焦超声治疗子宫肌瘤效果的超声造影与MRI相关因素分析[J]. 肿瘤影像学, 2018, 27(2): 103-108 DOI：

摘要

目的：

探讨影响高强度聚焦超声（high intensity focused ultrasound，HIFU）治疗子宫肌瘤效果的超声造影（contrast-enhanced ultrasound，CEUS）与MRI相关参数。

方法：

对49例子宫肌瘤患者在HIFU治疗前、治疗后进行CEUS及MRI检查，对患者的临床资料、检查结果及疗效进行分析。术前分析患者年龄，靶皮距，肌瘤位置、类型、体积，CEUS达峰时间（time to peak，TTP）、达峰强度（peak intensity，PI）、增强形态，MRI T2WI信号强度及增强程度，术后评估病灶消融率。

结果：

HIFU治疗的49例子宫肌瘤中，35例消融率70%，14例70%。Logistic回归分析发现，TTP、PI、T2WI信号强度、MRI增强程度与HIFU治疗子宫肌瘤疗效相关（

0.05）。

结论：

子宫肌瘤的CEUS及MRI相关参数TTP、PI、MRI T2WI信号强度及MRI增强程度是HIFU治疗消融率的独立影响因素，可用于预测HIFU治疗子宫肌瘤的疗效。

Abstract

Objective:

To explore the contrast-enhanced ultrasound (CEUS) and MRI factors influencing the therapeutic effects of high intensify focused ultrasound (HIFU) in the treatment of hysteromyoma.

Methods:

Forty-nine patients with hysteromyoma were examined by CEUS and MRI before and after HIFU treatment. The data of patients age

target-skin distance

hysteromyoma location

type

volume

time to peak (TTP)

peak intensity

enhanced morphology of CEUS

signal intensity of preexisting T2-weighted and enhancement degree of MR images were analyzed respecti

vely. After HIFU treatment

non-perfused volume (NPV) was observed.

Results:

After HIFU treatment

35 cases had NPV ratio 70%

and 14 cases had NPV ratio 70%. Logistic analysis showed that TTP

peak intensity

signal intensity of preexisting T2-weighted and enhancement degree of MR images were associated with HIFU efficiency (

0.05).

Conclusion:

TTP

peak intensity

signal intensity of preexisting T2-weighted and enhancement degree of MR images could affect HIFU efficiency in the treatment of hysteromyoma

and may be used to predict the therapeutic effects of HIFU.

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