The application of contrast-enhanced ultrasound combined with acoustic elastography in differential diagnosis of TI-RADS 4 lesions

LI Jieji; LI Huili; ZHOU Haiyan; LUO Baoming

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The application of contrast-enhanced ultrasound combined with acoustic elastography in differential diagnosis of TI-RADS 4 lesions

更新时间：2026-06-18

- The application of contrast-enhanced ultrasound combined with acoustic elastography in differential diagnosis of TI-RADS 4 lesions
- Vol. 24, Issue 4, Pages: 254-258(2015)
- 作者机构：
  
  1. 深圳市宝安区妇幼保健院超声科,广东,深圳,518000
  2. 中山大学孙逸仙纪念医院超声科,广东,广州,510120
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：19 January 2016，
  
  Published：2015
- 稿件说明：
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李杰基,李慧丽,周海燕,等. 超声造影联合弹性成像评价TI-RADS 4类甲状腺结节良恶性的应用研究[J]. 肿瘤影像学, 2015, 24(4): 254-258
DOI：

李杰基,李慧丽,周海燕,等. 超声造影联合弹性成像评价TI-RADS 4类甲状腺结节良恶性的应用研究[J]. 肿瘤影像学, 2015, 24(4): 254-258 DOI：

摘要

目的：

探讨超声造影(contrast-enhanced ultrasound

CEUS)联合声弹性成像(acoustic elastography，AE)在甲状腺超声影像报告和数据系统(Thyriod Imaging Reporting and Data System，TI-RADS)4类甲状腺结节良恶性鉴别诊断中的应用价值。

方法：

回顾性分析120例甲状腺结节患者共144个TI-RADS 4类结节性病灶的常规超声检查、AE及CEUS资料，以病理检查结果为金标准，构建受试者工作特征(receiver operating characteristic，ROC)曲线，比较CEUS、AE及CEUS联合AE对TI-RADS 4类甲状腺结节良恶性的鉴别诊断价值。

结果：

CEUS、AE对TI-RADS 4类甲状腺结节病灶的灵敏度、特异度、准确率分别为89.86%、86.67%、88.19%和81.16%、81.33%、81.25%，CEUE联合AE的灵敏度、特异度、准确率分别为94.20%、92.00%、93.06%，联合诊断效率最高，差异有统计学意义(

0.05)。

结论：

CEUS联合AE有助于提高鉴别TI-RADS 4类甲状腺结节良恶性的准确率。

Abstract

Objective:

To investigate the value of contrast-enhanced ultrasound (CEUS) combined with acoustic elastography in differential diagnosis of Thyroid Imaging Reporting and Data System (TI-RADS) 4 lesions.

Methods:

The routine ultrasound

acoustic elastography and CEUS data of 120 patients with a total 144 TI-RADS 4 lesions were retrospectively analyzed. The pathological findings were set as the gold standard to build the receiver operating characteristic (ROC) curve. Then the values of CEUS

acoustic elastography and CEUS combined with acoustic elastography in differential diagnosis of TI-RADS 4 lesions were compared.

Results:

The sensitivity

specificity and accuracy were 89.96%

86.67%

88.19% for CEUS; 81.16%

81.33%

81.25% for acoustic elastography; and 94.20%

92.00%

93.06% for CEUS combined with acoustic elastography. The combination of two methods had the highest diagnostic efficacy

with significant difference (

0.05).

Conclusion:

CEUS combined with acousticTIelastography is helpful in differentiating benign and malignant TI-RADS 4 lesions.

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