Clinical value of transrectal ultrasonography-guided biopsy combined with complexed prostate-specific antigen detection in diagnosis of prostate cancer

ZHU Xueping; ZHANG Lijie; CHEN Yanjun; ZHU Qianxiong; MAO Jinyu; DING He; GENG He; ZHANG Tao; YUAN Ya; ZHANG Yuna; HU Haiqiang

您当前的位置：

首页 >

文章列表页 >

Clinical value of transrectal ultrasonography-guided biopsy combined with complexed prostate-specific antigen detection in diagnosis of prostate cancer

更新时间：2026-06-18

- Clinical value of transrectal ultrasonography-guided biopsy combined with complexed prostate-specific antigen detection in diagnosis of prostate cancer
- Vol. 24, Issue 2, Pages: 134-137(2015)
- 作者机构：
  
  1. 上海市普陀区人民医院超声医学科,上海,200060
  2. 上海市普陀区人民医院泌尿外科,上海,200060
  3. 上海市普陀区人民医院病理科,上海,200060
  4. 上海市普陀区人民医院核医学科,上海,200060
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：10 August 2015，
  
  Published：10 August 2015
- 稿件说明：
移动端阅览
朱雪萍,章丽洁,陈燕君,等. 经直肠超声引导下经会阴前列腺穿刺活检联合复合前列腺特异抗原检测在前列腺癌诊断中的应用[J]. 肿瘤影像学, 2015, 24(2): 134-137
DOI：

朱雪萍,章丽洁,陈燕君,等. 经直肠超声引导下经会阴前列腺穿刺活检联合复合前列腺特异抗原检测在前列腺癌诊断中的应用[J]. 肿瘤影像学, 2015, 24(2): 134-137 DOI：

摘要

目的：

探讨经直肠超声引导下经会阴前列腺10点穿刺法加可疑灶定点穿刺活检联合复合前列腺特异抗原(cPSA）检测在前列腺癌诊断中的临床应用价值。

方法：

147例临床拟诊前列腺癌患者在前列腺穿刺前行血清cPSA检测，采用经直肠超声引导下经会阴前列腺10点穿刺法加可疑灶定点穿刺活检术。

结果：

经直肠超声引导下经会阴前列腺10点穿刺法加可疑灶定点穿刺活检取材准确率为100%。147例临床拟诊患者前列腺癌穿刺活检阳性率为38.8％(57/147)，其cPSA检测临界点为7.6 ng/mL。cPSA7.6 ng/mL 79例，诊断前列腺癌的灵敏度为93.8%，特异度为72.2%，前列腺穿刺活检阳性率达68.4%(54/79)，46.3%的患者(68/147)可避免穿刺活检。

结论：

经直肠超声引导下经会阴前列腺10点穿刺法加可疑灶定点穿刺是一种安全可靠的诊断技术，cPSA以7.6 ng/mL为临界点，可显著增加前列腺穿刺活检的阳性率。

Abstract

Objective:

To evaluate the clinical value of transrectal ultrasonography (TRUS)-guided 10-core plus fixed-point prostate biopsy combined with complexed prostate-specific antigen (cPSA) detection in the diagnosis of prostate cancer.

Methods:

cPSA was examined in 147 patients with suspected prostate cancer. All the patients underwent 10-core plus fixed-point prostate biopsy under the guidance of TRUS.

Results:

The accuracy of biopsy sampling was 100%. The positive rate of puncture biopsy was 38.8% (57/147) in 147 cases. The cutoff of cPSA was 7.6 ng/mL. There were 7

9 cases with cPSA more than or equal to 7.6 ng/mL. The specificity was 93.8% and the sensitivity was 72.2% for detecting prostate cancer when cPSA more than or equal to 7.6 ng/mL

and the positive rate of prostate biopsy was 68.4% (54/79). Puncture biopsy could be avoided in 46.3% (68/147) patients.

Conclusion:

TRUS-guided 10-core plus fixed-point prostate biopsy is a safe and reliable diagnostic method. When combined with cPSA with a cutoff of 7.6 ng/mL it can significantly increase the positive rate of prostate biopsy.

关键词

Keywords

references

Views

1814

下载量

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

The value of transrectal ultrasound fusion with mpMRI navigation combined with elastography-guided targeted prostate biopsy

Intratumoural and peritumoural mpMRI-based Delta-radiomics model for the prediction of the response to androgen deprivation therapy in prostate cancerLI Rong1, WANG Ting1, LÜ Hong2, LIU Xiaohang1, ZHOU Liangping1, GU Yajia1, ZHOU Bingni1

Evaluation of prostate cancer across different treatment stages using 18F-FDG PET imaging

A comparative study of 68Ga-TBM-001 PET/CT and 99mTc-MDP bone scintigraphy in the diagnosis of bone metastases of prostate cancer

Advances in the application of ultrasound artificial intelligence in prostate cancer

Related Author

Anyu LI

Zheng ZHU

Qi MA

李榕

王婷

吕泓

刘晓航

周良平

Related Institution

Department of Ultrasound, The Second Affiliated Hospital of Soochow University

Department of Ultrasound, Soochow University Affiliated Taicang First People's Hospital

Department of Pathology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University

Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University

Clinical Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences

AI问答

⁰