Value of <sup>18</sup>F-fluorodeoxyglucose PET/CT in differential diagnosis and staging of pancreatic neoplasm

YU Jiangyuan; LI Nan; FAN Yang; CHEN Puyun; WANG Xuejuan; ZHOU Nina; ZHANG Yan; ZHAO Wei; YANG Zhi

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Value of ¹⁸F-fluorodeoxyglucose PET/CT in differential diagnosis and staging of pancreatic neoplasm

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- Value of ¹⁸F-fluorodeoxyglucose PET/CT in differential diagnosis and staging of pancreatic neoplasm
- Vol. 24, Issue 3, Pages: 201-204(2015)
- 作者机构：
  
  1. 北京大学肿瘤医院暨北京市肿瘤防治研究所核医学科,北京,100142
  2. 恶性肿瘤发病机制及转化研究教育部重点实验室,北京,100142
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：20 October 2015，
  
  Published：20 October 2015
- 稿件说明：
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于江媛,李囡,范洋,等. ¹⁸F-脱氧葡萄糖PET/CT在胰腺占位诊断与分期中的价值[J]. 肿瘤影像学, 2015, 24(3): 201-204
DOI：

于江媛,李囡,范洋,等. ¹⁸F-脱氧葡萄糖PET/CT在胰腺占位诊断与分期中的价值[J]. 肿瘤影像学, 2015, 24(3): 201-204 DOI：

摘要

目的：

探讨

F-脱氧葡萄糖（

F-FDG）PET/CT在胰腺肿瘤鉴别诊断与分期中的作用和价值。

方法：

回顾性分析治疗前拟诊胰腺肿瘤，并在检查后4周内获得病理学结果的66例患者的

F-FDG PET/CT检查资料。

结果：

恶性组病灶最大标准摄取值(SUVmax)为2.2~21.6(平均6.453.44)，低度恶性组病灶SUVmax为2.4~12.8(平均7.043.65)，良性组病灶SUVmax为2.0~2.6(平均2.300.29)，其中恶性组与良性组、低度恶性组与良性组的SUVmax比较差异均具有统计学意义(

值分别为0.02及0.003)，而恶性组与低度恶性组SUVmax比较差异无统计学意义(

=0.662)。PET/CT对N分期的判断欠满意，但21.0%(13/62)病例因PET/CT发现远处转移而改变了治疗决策。

结论：

F-FDG PET/CT有助于胰腺占位的良恶性鉴别，虽然在胰腺癌区域淋巴结的检出和判断方面不具备显著优势，但对M分期的准确评估使相当一部分患者获得了最优化的治疗。

Abstract

Objective:

To evaluate the value of 18F-fluorodeoxyglucose (

F-FDG) PET/CT in differential diagnosis and staging of pancreatic neoplasms.

Methods:

A total of 66 patients who underwent

F-FDG PET/CT examination for suspected pancreatic neoplasms were confirmed with pathology.

Results:

The maximal standardized uptake value (SUVmax) in malignant group was 2.2-21.6 (6.453.44) and in low-grade malignant group was 2.4-12.8(7.043.65)

and in benign group was 2.0-2.6 (2.300.29). The SUVmax

was significantly different between benign group and malignant group (

=0.02) or low-grade malignant group(

=0.003). There was no significant difference in SUVmax between malignant group and low-grade malignant group. PET/CT changed 21% patients therapy plan.

Conclusion:

PET/CT is a useful tool in the differential diagnosis of benign from malignant pancreatic diseases

and helps to make a more accurate clinical decision.

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Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University

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Department of Pathology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University

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Value of 18F-fluorodeoxyglucose PET/CT in differential diagnosis and staging of pancreatic neoplasm

DOI：

摘要

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Value of ¹⁸F-fluorodeoxyglucose PET/CT in differential diagnosis and staging of pancreatic neoplasm