Application of contrast-enhanced ultrasound in differential diagnosis of benign and malignant breast tumors

WANG Jing; SHI Qiusheng; LI Gang; WU Rong; DU Lianfang

doi:10.19732/j.cnki.2096-6210.2019.03.004

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Application of contrast-enhanced ultrasound in differential diagnosis of benign and malignant breast tumors

更新时间：2025-12-15

- Application of contrast-enhanced ultrasound in differential diagnosis of benign and malignant breast tumors
- Vol. 28, Issue 3, Pages: 145-148(2019)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2019.03.004
  CLC：
- Published Online：19 July 2019，
  
  Published：19 July 2019
- 稿件说明：
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王晶,史秋生,李刚,等. 超声造影在乳腺良恶性肿瘤鉴别诊断中的应用[J]. 肿瘤影像学, 2019, 28(3): 145-148 https://doi.

org/10.19732/j.cnki.2096-6210.2019.03.004
王晶,史秋生,李刚,等. 超声造影在乳腺良恶性肿瘤鉴别诊断中的应用[J]. 肿瘤影像学, 2019, 28(3): 145-148 https://doi. DOI： 10.19732/j.cnki.2096-6210.2019.03.004.

org/10.19732/j.cnki.2096-6210.2019.03.004 DOI：

摘要

目的：

探讨超声造影技术在乳腺良恶性肿瘤鉴别诊断中的价值。

方法：

回顾性分析215例乳腺肿瘤患者232个病灶的超声造影特征。比较乳腺良恶性肿瘤的下述超声造影特征：造影后肿块的增强程度、边界、形态、灌注是否均匀、是否有内部灌注缺损及是否有穿支血管。

结果：

以术后病理学检查结果为金标准，232个病灶中131个病灶诊断为良性，101个诊断为恶性。而对应的超声造影结果显示，26例良性病灶诊断错误，5例恶性病灶诊断错误。以此计算出灵敏度为95.0%，特异度为80.2%，准确率为86.6%，阳性似然比为4.80，阴性似然比为0.062。

结论：

乳腺良恶性肿瘤在超声造影后表现出不同的特征。基于超声造影技术对乳腺良恶性肿瘤进行鉴别诊断的方法具有较高的灵敏度、特异度和准确率，可作为乳腺肿瘤良恶性快速、有效的鉴别诊断方法。

Abstract

Objective:

To investigate the value of contrast-enhanced ultrasound (CEUS) technology in the differential diagnosis of benign and malignant breast tumors.

Methods:

A total of 215 cases with 232 lesions that had been proved by pathological diagnosis results were studied. All the patients were examined by CEUS. The following contrast-enhanced ultrasonography characteristics of benign and malignant breast tumors was compared: the degree of enhancement of the tumor

the boundary and the shape of tumor

the uniform of perfusion

the internal perfusion defect

the perforator vessel.

Results:

According to the po

stoperative pathological results as the gold standard

131 of the 232 lesions were diagnosed as benign and 101 were diagnosed as malignant. The dynamic responses of benign and malignant breast tumors were significantly different under the CEUS. By observing the characteristics of lesions

26 cases of benign lesions were misdiagnosed

and 5 cases of malignant lesions were misdiagnosed. The calculated sensitivity

specificity

accuracy

positive likelihood ratio and negative likelihood ratio were 95.0%

80.2%

86.6%

4.80 and 0.062 respectively.

Conclusion:

Benign and malignant breast tumors show different characteristics after contrast-enhanced ultrasonography. The CEUS method has high sensitivity

specificity and accuracy in the differential diagnosis of benign and malignant breast tumors

and it can be used as a rapid and effective method in diagnosis of breast tumors.

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