Objective:

To investigate the magnetic resonance imaging (MRI) manifestations

clinical and pathological features of alveolar soft-part sarcoma (ASPS).

Methods:

The clinical data of 6 patients with ASPS confirmed by surgery and pathology from 2011 to 2018 were retrospectively analyzed

and all patients underwent MRI examination. Its clinical manifestations

imaging and pathological features were comprehensively analyzed.

Results:

Among 6 patients

1 case occurred in front of

ear

2 cases in tongue and 3 cases in limbs. The mass was round or nearly round

and the T1WI was equisignal or slightly high signal. The T2WI was non-uniform high signal; large and tortuous empty vascular shadows were seen in and around the tumorthe dispersion was high signal. Diffusion-weighted imaging (DWI) showed high signal unevenness

and the enhancement was non-uniform enhancement. Microscopically

the tumor cells were polygonal

with round nuclei

visible nucleoli and abundant cytoplasm. The positive rate of immunohistochemistry was higher: TFE3 (3/3)

NSE (4/6)

MyoD1 (3/6).

Conclusion:

ASPS has characteristic MRI manifestations and clinical characteristics

which are more common in young women and tend to occur in soft tissues deep in the limbs

with large volume

equal or slightly high signal on T1WI

and large

tortuous empty vascular shadow in and around the tumor on T2WI. The prognosis is poor and metastasis is very likely to occur.