Comparison between ultrasonic and pathological features and misdiagnosis analysis in breast f ibromatosis

ZONG Qingqing; DENG Jing; XU Di

doi:10.19732/j.cnki.2096-6210.2019.06.006

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Comparison between ultrasonic and pathological features and misdiagnosis analysis in breast f ibromatosis

更新时间：2025-12-15

- Comparison between ultrasonic and pathological features and misdiagnosis analysis in breast f ibromatosis
- Vol. 28, Issue 6, Pages: 384-389(2019)
- 作者机构：
  
  1. 南京医科大学第一附属医院超声医学科,南京,210029
  2. 南京医科大学第一附属医院老年医学科,南京,210029
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2019.06.006
  CLC：
- Published Online：28 December 2019，
  
  Published：28 December 2019
- 稿件说明：
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宗晴晴,邓晶,许迪. 乳腺纤维瘤病超声表现与病理结果对照研究及误诊分析[J]. 肿瘤影像学, 2019, 28(6): 384-389 https://doi.

org/10.19732/j.cnki.2096-6210.2019.06.006
宗晴晴,邓晶,许迪. 乳腺纤维瘤病超声表现与病理结果对照研究及误诊分析[J]. 肿瘤影像学, 2019, 28(6): 384-389 https://doi. DOI： 10.19732/j.cnki.2096-6210.2019.06.006.

org/10.19732/j.cnki.2096-6210.2019.06.006 DOI：

摘要

目的：

探讨乳腺纤维瘤病常规超声、弹性成像、超声造影特征及相应病理组织学特点，分析误诊原因，以提高诊断水平。

方法：

回顾并分析病理学检查证实的17例乳腺纤维瘤病患者（13例来源于乳腺实质，4例来源于胸壁）的临床、病理学资料及超声特征表现。

结果：

19个来源于乳腺实质的病灶，常规超声上呈形态不规则、边缘不光整的低回声。3个病灶超声造影以周边增强为主，内部呈均匀或不均匀低增强。11个病灶行弹性成像，5个弹性评分为3分，6个为4分。4个胸壁来源的病灶常规超声上多呈形态规则，边缘光整，1个病灶造影表现为边界清晰的高增强，范围无增大。

结论：

乳腺纤维瘤病影像学上易被误诊为恶性肿瘤，其超声表现与病理学特征密切相关。通过多模态综合评估对判断病灶的来源及鉴别诊断有一定价值，结合临床特征有助于进一步减少误诊率。

Abstract

Objective:

To investigate the ultrasonographic features and corresponding histopathological features of mammary f ibromatosis

and to analyze the causes of misdiagnosis in order to improve the diagnostic level.

Methods:

Clinicopathological data and ultrasonographic imaging features of 17 patients with pathologically conf irmed mammary f ibromatosis (13 from the breast parenchyma and 4 from the chest wall) were retrospectively analyzed.

Results:

Nineteen lesions originated from breast parenchyma

and conventional ultrasound showed hypoechoic with irregular edges

while contrast-enhanced ultrasonography showed

mainly peripheral enhancement. Elastography was performed in 11 lesions

with 5 cases scored 3 points and 6 scored 4 points. Four lesions originated from the chest wall were mostly regular in shape on conventional ultrasound and showed high enhancement with clear boundaries on contrast-enhanced ultrasonography.

Conclusion:

Mammary f ibromatosis is easily misdiagnosed as malignant tumor on imaging

and its ultrasonic manifestations are closely related to pathological features. Multimodal comprehensive evaluation is of certain value in judging the source of lesions and differential diagnosis

and combining with clinical features is helpful to further reduce the misdiagnosis rate.

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