Study on 7.0T small animal magnetic resonance imaging system T <sub>1 </sub>mapping uniformity with several common coils

QI Ming; ZHANG Jianping; ZHANG Yingjian

doi:10.19732/j.cnki.2096-6210.2020.02.017

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Study on 7.0T small animal magnetic resonance imaging system T ₁mapping uniformity with several common coils

更新时间：2025-12-15

- Study on 7.0T small animal magnetic resonance imaging system T ₁mapping uniformity with several common coils
- Vol. 29, Issue 2, Pages: 175-180(2020)
- 作者机构：
  
  1. 核物理与离子束应用教育部重点实验室,上海,200433
  2. 复旦大学生物医学影像研究中心,上海,200032
  3. 上海分子影像探针工程技术中心,上海,200032
  4. 上海市质子重离子医院核医学科,上海,201315
  5. 复旦大学附属肿瘤医院核医学科，复旦大学上海医学院肿瘤学系,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2020.02.017
  CLC：
- Published Online：28 April 2020，
  
  Published：28 April 2020
- 稿件说明：
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戚鸣,张建平,章英剑. 7.0T小动物磁共振成像系统几个常用线圈T ₁ mapping均匀性研究[J]. 肿瘤影像学, 2020, 29(2): 175-180 https://doi.

org/10.19732/j.cnki.2096-6210.2020.02.017
戚鸣,张建平,章英剑. 7.0T小动物磁共振成像系统几个常用线圈T ₁ mapping均匀性研究[J]. 肿瘤影像学, 2020, 29(2): 175-180 https://doi. DOI： 10.19732/j.cnki.2096-6210.2020.02.017.

org/10.19732/j.cnki.2096-6210.2020.02.017 DOI：

摘要

目的：

旨在评估7.0T小动物磁共振成像（magnetic resonance imaging，MRI）几个常用线圈采集T

mapping的均匀性。

方法：

分别用大/小鼠脑表面线圈、小鼠头/体部容积线圈测量去离子水、0.2 mmol/L及0.4 mmol/L马根维显溶液的T

mapping，并勾画多个感兴趣区（regions of interest，ROI），比较T

mapping空间均匀性。

结果：

不同线圈对

值的测量存在空间均匀性差异，并且特定情况下容积线圈中T

mapping差异比信号强度差异更灵敏。总体而言，小口径线圈均匀性优于大口径线圈；X方向（左右）均匀性相对较好，优于Y方向（上下）均匀性。

结论：

建议将T

mapping均匀性作为质控参考指标之一。采集T

mapping时尽可能采用小口径线圈。当实验动物采用仰卧或俯卧位时，选取对侧组织

值作对比具有更高的可信度。

Abstract

Objective:

To assess the uniformity of T

mapping acquired by several commonly used coils of 7.0T small animal magnetic resonance imaging (MRI).

Methods:

mapping of deionized water

0.2 mmol/L and 0.4 mmol/L Magnevist solution was measured with rat/mouse brain surface coil and mouse head/body volume coil

and multiple regions of interest (ROI) were delineat-ed. And the T

mapping spatial

uniformity of different coils were compared.

Results:

There are spatial uniformity differences in the measurement of

values by different coils. In certain cases

the difference in T

mapping in the volume coils is more sensitive than the difference in signal strength. In general

the uniformity of small-diameter coils is better than that of large-diameter coils. And the uniformity of X-direction (left to right) is better than the Y-direction (upper to lower).

Conclusion:

We recommend T

mapping uni-formity as one of the quality control reference indicators. Small diameter coils should be used when acquiring T

mapping. When the experimental animals were in the supine or prone position

the

values of the contralateral tissues should be selected for comparison with higher confidence.

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Study on 7.0T small animal magnetic resonance imaging system T 1 mapping uniformity with several common coils

DOI：10.19732/j.cnki.2096-6210.2020.02.017

摘要

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references

Study on 7.0T small animal magnetic resonance imaging system T ₁mapping uniformity with several common coils