Efficacy and safety analysis of ultrasound-guided percutaneous transhepatic microwave ablation in the treatment of liver cancers

LIU Guotao; ZHU Zheng; NI Qingfeng; SHEN Bo; WU Xiaoman; ZHANG Yuhang; ZHOU Chao; DONG Xueming; WANG Wenping; LI Weiping

doi:10.19732/j.cnki.2096-6210.2020.05.012

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Efficacy and safety analysis of ultrasound-guided percutaneous transhepatic microwave ablation in the treatment of liver cancers

更新时间：2025-12-15

- Efficacy and safety analysis of ultrasound-guided percutaneous transhepatic microwave ablation in the treatment of liver cancers
- Vol. 29, Issue 5, Pages: 495-499(2020)
- 作者机构：
  
  1. 太仓市第一人民医院超声科，江苏太仓,215400
  2. 复旦大学附属中山医院超声科,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2020.05.012
  CLC：
- Published Online：28 October 2020，
  
  Published：28 October 2020
- 稿件说明：
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刘国涛,朱正,倪庆丰,等. 超声引导下经皮经肝微波消融术治疗肝癌的疗效及安全性分析[J]. 肿瘤影像学, 2020, 29(5): 495-499 https://doi.

org/10.19732/j.cnki.2096-6210.2020.05.012
刘国涛,朱正,倪庆丰,等. 超声引导下经皮经肝微波消融术治疗肝癌的疗效及安全性分析[J]. 肿瘤影像学, 2020, 29(5): 495-499 https://doi. DOI： 10.19732/j.cnki.2096-6210.2020.05.012.

org/10.19732/j.cnki.2096-6210.2020.05.012 DOI：

摘要

目的：

评估超声引导下经皮经肝微波消融治疗肝癌的治疗效果及安全性。

方法：

回顾并分析2015年4月2020年1月江苏省太仓市第一人民医院采用超声引导下行微波消融术治疗的35例（共49个病灶）原发性或转移性肝癌患者，术后定期随访超声造影及肝功能指标丙氨酸氨基转移酶（ALT）评价治疗效果以及肝脏损伤情况；以及观察并发症发生情况。

结果：

术后即时超声造影显示所有病灶均完全灭活。术后超声造影随访结果：3个月肝内未见复发；6个月原肿瘤消融部位复发2例；至9及12个月原肿瘤消融部位复发仍为2例，无新增复发患者。术后1周ALT较术前明显上升（

＜0.05），术后1及3个月复查ALT均降至术前相仿水平（

＞0.05）。消融术并发症：术中1例因疼痛致手术暂停，休息5 min缓解后继续手术；术后切口或右上腹轻度不适15例；术后1周内发热23例；术后胸腔少量积液3例；术后腹腔出血1例。

结论：

采用超声引导下经皮经肝微波消融技术治疗肝癌是安全可行的，可取得比较满意的治疗效果，值得临床推广使用。

Abstract

To evaluate the efficacy and safety of ultrasound-guided percutaneous transhepatic microwave ablation in the treatment of liver cancer.

Methods:

Retrospective analysis of 35 cases (49 lesions) of primary or metastatic liver cancer treated by ultrasound- guided microwave ablation in Taicang First People's Hospital from Apr. 2015 to Jan. 2020

regular postoperative follow-up of contrast-enhanced ultrasonography (CEUS) and hepatic function (ALT) were performed to evaluate the therapeutic effect and liver injury

and to observe the complications.

Results:

All the lesions were completely inactivated by CEUS after operation. The results of follow-up showed that there was no recurrence in the liver at 3 months. There were 2 cases with recurrence of the original ablation site at 6 months

and no new cases at 9 months and 12 months. ALT increased significantly at 1 week after operation (

＜0.05)

and decreased to the same level at 1 month and 3 months after operation (

＞0.05). The complications of ablation included 1 case was stopped during operation due to pain

rest for 5 min; 15 cases had slight discomfort in incision or right upper abdomen; 23 cases had fever within 1 week after operation; 3 cases had small pleural effusion after operation; 1 case of postoperative abdominal hemorrhage.

Conclusion:

Ultrasound-guided percutaneous microwave ablation is a safe and effective method for the treatment of liver cancer. It is worthy of clinical application.

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