Retrospective analysis of the application value of fMRI and DTI in functional glioma surgery

NI Weijuan; WANG Chao; NI Dianjun; LI Guisu

doi:10.19732/j.cnki.2096-6210.2021.02.009

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Retrospective analysis of the application value of fMRI and DTI in functional glioma surgery

更新时间：2025-12-15

- Retrospective analysis of the application value of fMRI and DTI in functional glioma surgery
- Vol. 30, Issue 2, Pages: 108-113(2021)
- 作者机构：
  
  1. 深圳市龙华区人民医院神经内科,广东,深圳,518109
  2. 杭州市肿瘤医院神经外科,浙江,杭州,310000
  3. 深圳市龙华区人民医院神经外科,广东,深圳,518109
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2021.02.009
  CLC：
- Published Online：28 April 2021，
  
  Published：28 April 2021
- 稿件说明：
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倪卫娟,王超,倪殿军,等. fMRI和DTI在功能区胶质瘤手术中的应用价值[J]. 肿瘤影像学, 2021, 30(2): 108-113 https://doi.

org/10.19732/j.cnki.2096-6210.2021.02.009
倪卫娟,王超,倪殿军,等. fMRI和DTI在功能区胶质瘤手术中的应用价值[J]. 肿瘤影像学, 2021, 30(2): 108-113 https://doi. DOI： 10.19732/j.cnki.2096-6210.2021.02.009.

org/10.19732/j.cnki.2096-6210.2021.02.009 DOI：

摘要

目的：

分析功能磁共振成像（functional magnetic resonance imaging，fMRI）和弥散张量成像（diffusion tensor imaging，DTI）在功能区胶质瘤手术中的指导价值。

方法：

收集2018年1月2019年1月于深圳市龙华区人民医院接受手术治疗的50例功能区胶质瘤患者的临床资料，统计患者的DTI、fMRI检查结果和手术结果。

结果：

高级别胶质瘤的部分各向异性（fractional anisotropy，FA）值和表观扩散系数（apparent diffusion coefficient，ADC）值与低级别胶质瘤相比有差异（

=9.128、8.535，

＜0.05）。高级别胶质瘤的纤维束破坏形态发生率明显高于低级别胶质瘤（

=4.393，

＜0.05），纤维束移位率明显低于低级别胶质瘤（

=4.462，

＜0.05）。41例（82.00%）患者的肿瘤病灶完全切除，高级别胶质瘤患者的完全切除率和生存率均明显低于低级别胶质瘤（

=5.378，

＜0.05），复发率高于低级别胶质瘤（

=4.303，

＜0.05）。不同级别胶质瘤患者手术后的生存质量评分均明显高于手术前，且低级别胶质瘤患者术后的生存质量评分高于高级别胶质瘤（

=10.812、15.224、19.485，

＜0.05）。

结论：

术前fMRI联合DTI技术进行功能区胶质瘤分级，对提高肿瘤病灶的完全切除率，降低死亡率和复发率有重要意义。

Abstract

Objective：

To retrospectively analyze the guiding value of functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) in functional glioma surgery.

Methods:

The clinical data of 50 patients

with functional glioma who underwent surgical treatment in Shenzhen Longhua Peoples Hospital from January 2018 to January 2019 were collected for retrospective analysis

and the DTI

fMRI examination results and surgical results of the patients were collected.

Results：

The fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of high-grade gliomas were different from those of low-grade gliomas (

9.128

8.535

＜0.05). The incidence of fiber bundle destruction in high-grade gliomas was significantly higher than that of low-grade gliomas gliomas (

=4.393

＜0.05)

and the fiber bundle displacement rate was significantly lower than that of low-grade glioma (

=4.462

＜0.05). 41 patients (82.00%) had complete resection of tumor lesions. The complete resection rate and survival rate of patients with high-grade glioma were significantly lower than that of low-grade glioma (

=5.378

＜0.05)

and the recurrence rate was higher than that of low-grade glioma (

=4.303

＜0.05). The quality of life scores of patients with different grades of glioma after surgery were significantly higher than those before surgery

and the quality of life scores of patients with low-grade gliomas were higher than those of high-grade gliomas (

=10.812

15.224

19.485

＜0.05).

Conclusion：

Preoperative fMRI combined with DTI technology for grading functional gliomas is of great significance for improving the complete resection rate of tumor lesions and reducing the mortality and recurrence rate.

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