CT and MRI features of pancreatic neuroendocrine neoplasm

WANG Mingliang; JI Yuan; YAO Xiuzhong; ZENG Mengsu

doi:10.19732/j.cnki.2096-6210.2021.04.003

您当前的位置：

首页 >

文章列表页 >

CT and MRI features of pancreatic neuroendocrine neoplasm

更新时间：2025-12-15

- CT and MRI features of pancreatic neuroendocrine neoplasm
- Vol. 30, Issue 4, Pages: 245-251(2021)
- 作者机构：
  
  1. 复旦大学附属中山医院放射科,上海,200032
  2. 复旦大学附属中山医院病理科,上海,200032
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2021.04.003
  CLC：
- Published Online：28 August 2021，
  
  Published：28 August 2021
- 稿件说明：
移动端阅览
王明亮,纪元,姚秀忠,等. 胰腺神经内分泌肿瘤的CT和MRI特征[J]. 肿瘤影像学, 2021, 30(4): 245-251 https://doi.

org/10.19732/j.cnki.2096-6210.2021.04.003
王明亮,纪元,姚秀忠,等. 胰腺神经内分泌肿瘤的CT和MRI特征[J]. 肿瘤影像学, 2021, 30(4): 245-251 https://doi. DOI： 10.19732/j.cnki.2096-6210.2021.04.003.

org/10.19732/j.cnki.2096-6210.2021.04.003 DOI：

摘要

目的：

探讨胰腺神经内分泌肿瘤（pancreatic neuroendocrine neoplasm，pNEN）的计算机体层成像（computed tomography，CT）和磁共振成像（magnetic resonance imaging，MRI）特征。

方法：

回顾并分析2009年2月2020年9月经手术后病理学检查证实为pNEN的143例患者的CT和MRI资料，将病灶分为神经内分泌瘤（neuroendocrine tumor，NET）G1、NET G2、NET G3和神经内分泌癌（neuroendocrine carcinoma，NEC）G3共4组。图像分析包括肿瘤位置、大小、形状、边缘、密度或信号强度、增强特征、主胰管扩张、周围侵犯及有无转移等。

结果：

143例患者共检出149个病灶，NET G1、NET G2、NET G3、NEC G3病灶数分别为63、74、8、4个。NET G1组病灶最小（平均为2.24 cm），NEC G3组病灶最大（平均为5.75 cm）；类圆形病灶为127个（85.2%），不规则形病灶为22个（14.8%）；130个（87.2%）病灶CT平扫为等密度，19个（12.8%）病灶呈稍低密度；124个（83.2%）病灶为T2加权成像（T2-weighted imaging，T2WI）高或稍高信号；146个（98.0%）病灶实性区为T1加权成像（T1-weighted imaging，T1WI）低或稍低信号；130个病灶实性区弥散加权成像（diffusion-weighted imaging，DWI）均表现为高信号；边缘清晰76个（51.0%）；囊变57个（38.3%）；病灶内钙化22个（14.8%）；胰管扩张14个（9.4%）；远端胰腺萎缩9个（6.0%）；胰周侵犯30个（20.1%）；淋巴结转移14个（9.4%）；肝转移15个（10.1%）。92个（61.8%）病灶CT增强呈持续显著强化；115个（77.2%）病灶MRI增强呈明显强化，随时间延长呈持续性强化，NEC G3的4个（100.0%）病灶在CT和MRI增强均表现为动脉期轻度强化，随时间延长强化程度稍增加，但始终低于胰腺组织。

结论：

pNEN的典型CT和MRI表现为类圆形的实性结节或肿块，CT平扫呈等或稍低密度，T1WI低或稍低信号，增强后大多数低级别肿瘤呈明显持续强化，高级别肿瘤多数强化程度较低，接近或稍低于周围胰腺。

Abstract

Objective:

To investigate the

computed tomography (CT) and magnetic resonance imaging (MRI) features of pancreatic neuroendocrine neoplasm (pNEN).

Methods:

CT and MRI data of 143 patients with pNEN confirmed by surgery and pathology from February 2009 to September 2020 were retrospectively analyzed. The lesions were divided into four groups including neuroendocrine tumor (NET) G1

NET G2

NET G3 and neuroendocrine carcinoma (NEC) G3. Image analysis included tumor location

size

shape

edge

density or signal intensity

enhancement characteristics

main pancreatic duct dilatation

peripheral invasion and metastasis.

Results:

A total of 149 lesions were detected in 143 patients. The number of NET G1

NET G2

NET G3 and NEC G3 lesions was 63

8 and 4

respectively. NEC G3 group had the largest lesion (average diameter was 5.75 cm)

and NET G1 group had the smallest lesion (average diameter was 2.24 cm). There were 127 (85.2%) round-like lesions and 22 (14.8%) irregular lesions. 130 (87.2%) lesions were iso-density on CT plain scan

and 19 (12.8%) lesions were slightly low density. 124 (83.2%) lesions appeared hyperintense or slightly high signal intensity on T2-weighted imaging (T2WI)

146 (98.0%) lesions appeared moderately or slightly hypointense on T1-weighted imaging (T1WI)

and all 130 lesions showed high signal intensity on diffusion-weighted imaging (DWI). Clear margin in 76 (51.0%) lesions

cysts in 57 (38.3%) lesions

calcification in 22 (14.8%) lesions

pancreatic duct dilatation in 14 (9.4%) lesions

distal pancreatic atrophy in 9 (6.0%) lesions

peripancreatic invasion in 30 (20.1%) lesions

lymph node metastasis in 14 (9.4%) lesions

and liver metastasis in 15 (10.1%) lesions were found. After contrast-enhancement

92 (61.8%) lesions showed continuous significant enhancement on CT images

and 115 (77.2%) lesions showed obvious enhancement on arterial phase images with its degrees higher than the pancreas and continuous contrast-enhancement. Four lesions of NEC G3 appeared slightly contrast enha

ncement with degrees lower than the pancreas all the time.

Conclusion:

The typical CT and MRI manifestations of pancreatic neuroendocrine neoplasms are round-like nodules or masses. The lesions are equal or slightly low density on CT plain scan and low or slightly low signal intensity on T1WI. After contrast enhancement

most of the low-grade tumors showed obvious continuous enhancement

while most of the high-grade neoplasms showed slightly contrast enhancement on all phase images with its degrees lower than the pancreas.

关键词

Keywords

references

Views

1602

下载量

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Application value of multimodal imaging technology based on CT and MRI in the diagnosis and PRETEXT staging of childhood hepatoblastoma

The application value of CEUS-CT/MRI fusion image virtual navigation in the biopsy of diffuse liver carcinoma

Imaging analysis of 4 cases parosteal lipoma and literature review

Clinical, imaging and pathological features of desmoplastic small round cell tumor in abdominal and pelvic cavity

An update in the era of radiomics of pancreatic neuroendocrine neoplasm based on CT and MRI

Related Author

Liya LU

Xiao YU

Yanan LI

Qiancheng LI

Tao XIN

Chenglong LI

LI Qian

KONG Wentao

Related Institution

Department of Imaging, Xuzhou Children's Hospital

Department of Special Diagnosis, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University

Department of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University

Department of Ultrasound, Zhongshan Hospital, Fudan University

Department of Radiology, Minhang District Branch of Cancer Hospital, Fudan University

AI问答

⁰