The predictive value of pretreatment <sup>18</sup>F-FDG PET/CT in gastric MALT lymphoma

ZHOU Wenjing; JIANG Chong; TENG Yue; LAI Ruihe; JIA Peng; DING Chongyang; HE Jian

doi:10.19732/j.cnki.2096-6210.2022.02.010

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The predictive value of pretreatment ¹⁸F-FDG PET/CT in gastric MALT lymphoma

更新时间：2025-12-15

- The predictive value of pretreatment ¹⁸F-FDG PET/CT in gastric MALT lymphoma
- Vol. 31, Issue 2, Pages: 167-173(2022)
- 作者机构：
  
  1. 南京大学医学院附属鼓楼医院核医学科,南京,210008
  2. 南京医科大学第一附属医院核医学科,南京,210029
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2022.02.010
  CLC：
- Published Online：28 April 2022，
  
  Published：28 April 2022
- 稿件说明：
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周文婧,蒋冲,滕月,等. 治疗前¹⁸F-FDG PET/CT对胃MALT淋巴瘤的预测价值[J]. 肿瘤影像学, 2022, 31(2): 167-173 https://doi.

org/10.19732/j.cnki.2096-6210.2022.02.010
周文婧,蒋冲,滕月,等. 治疗前¹⁸F-FDG PET/CT对胃MALT淋巴瘤的预测价值[J]. 肿瘤影像学, 2022, 31(2): 167-173 https://doi. DOI： 10.19732/j.cnki.2096-6210.2022.02.010.

org/10.19732/j.cnki.2096-6210.2022.02.010 DOI：

摘要

目的：

探讨治疗前行

F-脱氧葡萄糖（

F-fluorodeoxyglucose，

F-FDG）正电子发射体层成像（positron emission tomography，PET）/计算机体层成像（computed tomography，CT）对胃黏膜相关淋巴样组织（mucosa-associated lymphoid tissue，MALT）淋巴瘤患者的疗效和预后的预测价值。

方法：

回顾并分析42例在治疗前行

F-FDG PET/CT扫描的初诊胃MALT淋巴瘤患者。

F-FDG PET/CT结果分析采用定性和半定量方法评估：视觉评估和最大标准摄取值（maximal standard uptake value，SUV

max

）评估。以无进展生存期（progression-free survival，PFS）为终点评价预后。

结果：

随访患者13~80个月，平均（38.916.5）个月，PET阳性、高SUV

max

与较差的PFS显著相关。多因素分析显示，SUV

max

是PFS的唯一独立预测因子（HR=11.283，

=0.022）。SUV

max

也可以独立预测疗效（OR=8.750，

=0.005）。

结论：

治疗前行

F-FDG PET/CT可以预测胃MALT淋巴瘤患者的疗效和预后。

Abstract

Objective:

To investigate the predictive value of pretreatment

F-fluorodeoxyglucose (

F-FDG) positron emission tomography (PET)/computed tomography (CT) for treatment response and survival outcomes in gastric mucosa-associated lymphoid tissue (MALT) lymphoma patients.

Methods:

orty-two patients with newly diagnosed gastric MALT lymphoma were retrospectively analyzed in this study. Each patient underwent

F-FDG PET/CT scans before treatment.

F-FDG PET/CT results were analyzed using qualitative and semi-quantitative assessment methods: visual assessment and maximal standardized uptake value (SUV

max

). Progression-free survival (PFS) was used as endpoints to evaluate prognosis.

Results:

Patients were followed for 13 to 80 months with a mean of (38.916.5) months. PET positivity and high SUV

max

were significantly associated with inferior PFS. Multivariate analysis showed that SUV

max

was the only independent predictor of PFS (HR=11.283

=0.022). SUV

max

could also independently predict the treatment response (OR=8.750

=0.005).

Conclusion:

Pretreatment

F-FDG PET/CT can predict treatment response and survival outcomes in gastric MALT lymphoma patients.

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The predictive value of pretreatment 18F-FDG PET/CT in gastric MALT lymphoma

DOI：10.19732/j.cnki.2096-6210.2022.02.010

摘要

Abstract

关键词

Keywords

references

The predictive value of pretreatment ¹⁸F-FDG PET/CT in gastric MALT lymphoma