CT signs and clinicopathological features of gastrointestinal stromal tumor

GU Yangchun; XUE Haiqiao

doi:10.19732/j.cnki.2096-6210.2022.03.012

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CT signs and clinicopathological features of gastrointestinal stromal tumor

更新时间：2025-12-15

- CT signs and clinicopathological features of gastrointestinal stromal tumor
- Vol. 31, Issue 3, Pages: 290-295(2022)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2022.03.012
  CLC：
- Published Online：28 June 2022，
  
  Published：28 June 2022
- 稿件说明：
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顾阳春,薛海桥. 胃肠道间质瘤CT征象及临床病理学特征分析[J]. 肿瘤影像学, 2022, 31(3): 290-295 https://doi.

org/10.19732/j.cnki.2096-6210.2022.03.012
顾阳春,薛海桥. 胃肠道间质瘤CT征象及临床病理学特征分析[J]. 肿瘤影像学, 2022, 31(3): 290-295 https://doi. DOI： 10.19732/j.cnki.2096-6210.2022.03.012.

org/10.19732/j.cnki.2096-6210.2022.03.012 DOI：

摘要

目的：

分析多层螺旋计算机体层成像（multi-slice spiral computed tomography，MSCT）下胃间质瘤（gastric stromal tumor，GST）与小肠间质瘤（small intestinal stromal tumor，SIST）的CT征象及病理学特征。

方法：

收集2016年9月2019年9月江苏省滨海人民医院诊治的117例胃肠道间质瘤（gastrointestinal stromal tumors，GIST）患者的临床资料。依据发病部位的不同将GIST患者分为GST组（83例）和SIST组（34例），对比分析两组患者CT征象和病理学特征。

结果：

83例GST患者术前主要临床表现为腹痛、腹胀等，部分患者出现黑便或便血等，其中原发于胃底55例，胃体26例，胃窦2例；34例SIST患者主要表现为黑便或便血、大便隐血试验阳性等，部分患者出现腹痛、腹胀等，其中原发于十二指肠7例，空肠21例，回肠6例。GST组肿瘤直径＜2 cm者占比明显高于SIST组［48.2%（40/83）

20.6%（7/34），

=7.647，

=0.006］。两组肿瘤内部情况、有无坏死或钙化等差异无统计学意义（

＜0.05），两组肿瘤形态及生长方式差异均有统计学意义（

＜0.05）。GST组动脉期、静脉期及延迟期增强扫描呈渐进性强化，SIST组动脉期增强扫描呈速升-缓降型强化。SIST组MSCT平扫及3期增强扫描CT值明显高于GST组（

＜0.05）。GST组CD34阳性率明显高于SIST组（

＜0.05），其他免疫组织化学指标差异均无统计学意义（

＞0.05）。SIST组患者病理学危险程度分级中高危患者占比明显高于GST组（

＜0.05）。

结论：

GST与SIST的CT征象及临床病理学特征均存在一定差异。

Abstract

Objective:

To analyze the computed tomography (CT) and pathology features of gastric stromal tumor (GST) and small intestinal stromal tumor (SIST) under multi-slice s

piral CT (MSCT).

Methods:

The clinical data of 117 patients with gastrointestinal stromal tumors (GIST) in Jiangsu Binhai peoples hospital from September 2016 to September 2019 were collected. Patients were divided into GST group (83 cases) and SIST group (34 cases) according to the location of GIST. The CT and pathological features of the two groups were compared and analyzed.

Results:

The main clinical manifestations of 83 GST patients before operation were abdominal pain

abdominal distension

and some patients had black stool or hematochezia

including 55 cases of primary gastric fundus

26 cases of gastric body

and 2 cases of gastric antrum. At the same time

34 cases of sist patients mainly manifested as black stool or hematochezia

stool occult blood test positive

and some patients had abdominal pain

abdominal distension

etc.

including 7 cases of primary duodenum

21 cases of jejunum

6 cases of ileum. The proportion of tumor diameter ＜2 cm in GST group was significantly higher than that in SIS Group ［48.2% (40/83)

20.6% (7/34)

=7.647

=0.006］. Tumor internal condition

necrosis or calcification between the two groups were no significant differences (

＜0.05)

but tumor morphology and growth pattern showed significant differences (

＞0.05). In GST group

the enhancement scan of arterial phase

venous phase and delayed phase showed gradual enhancement

while in SIS group

the enhancement scan of arterial phase showed fast rising- slowly decreasing enhancement. The CT values of MSCT plain scan and three-phase contrast-enhanced imaging in SIS group were significantly higher than those in GST group (

＜0.05). The positive rate of CD34 in GST group was significantly higher than that in SIST group (

＜0.05)

and there were no statistical differences in other immunohistochemical indexes (

＞0.05). The proportion ofhigh-risk patients in pathological risk grading in SIST group was significant

ly higher than that in GST group (

＜0.05).

Conclusion:

CT findings and pathological characteristics between GST and SIST were some differences.

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