Application value of conventional ultrasound and contrast-enhanced ultrasound in diagnostic of mummified thyroid nodule

CHEN Na; CHEN Songwang

doi:10.19732/j.cnki.2096-6210.2023.01.007

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Application value of conventional ultrasound and contrast-enhanced ultrasound in diagnostic of mummified thyroid nodule

更新时间：2025-12-15

- Application value of conventional ultrasound and contrast-enhanced ultrasound in diagnostic of mummified thyroid nodule
- Vol. 32, Issue 1, Pages: 47-52(2023)
- 作者机构：
- 作者简介：
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- DOI：10.19732/j.cnki.2096-6210.2023.01.007
  CLC：
- Published Online：28 February 2023，
  
  Published：28 February 2023
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陈娜,陈松旺. 常规超声及超声造影在诊断甲状腺木乃伊结节上的应用价值[J]. 肿瘤影像学, 2023, 32(1): 47-52 https://doi.

org/10.19732/j.cnki.2096-6210.2023.01.007
陈娜,陈松旺. 常规超声及超声造影在诊断甲状腺木乃伊结节上的应用价值[J]. 肿瘤影像学, 2023, 32(1): 47-52 https://doi. DOI： 10.19732/j.cnki.2096-6210.2023.01.007.

org/10.19732/j.cnki.2096-6210.2023.01.007 DOI：

摘要

目的：

探讨甲状腺木乃伊结节（mummified thyroid nodule，MTN）的常规超声和超声造影（contrast-enhanced ultrasound，CEUS）特点，以区别于恶性结节。

方法：

选取38例MTN患者和42例甲状腺乳头状癌（papillary carcinoma of the thyroid，PTC）患者，运用常规超声和CEUS获取结节的大小、内部回声、边界、纵横比、血流信号、钙化类型、钙化部位、有无双边征、增强模式等参数，比较两组间上述参数的差异，评价MTN特异性征象诊断MTN的效能。

结果：

MTN在随访过程中，体积明显减小，缩小率为（714）%，差异有统计学意义（

＜0.05）。两组间在纵横比、钙化类型、钙化部位、血流信号、双边征、增强模式上差异均有统计学意义（

＜0.05），两组间结节的内部回声及边界的差异无统计学意义（

＞0.05）。根据CEUS的无增强模式诊断MTN的特异度和阳性预测值均为100.00%。

结论：

对比既往超声检查，结合结节周边的粗大（弧形/环形/壳状）钙化、双边征及CEUS上为无增强模式的超声特征，有助于MTN的诊断，且CEUS诊断MTN的效能较高。

Abstract

Objective:

To explore the characteristic of conventional ultrasound and contrast-enhanced ultrasound (CEUS) of mummified thyroid nodule (MTN)

in order to avoid to misdiagnosis as malignant nodules.

Methods:

A total of 38 cases of MTN patients and 42 cases of papillary carcinoma of the thyroid (PTC) patients were enrolled. The size

echogenicity

margin

aspect ratio

blood flow signal

calcification morphology

calcification

location

double ring sign

and the enhancement patterns for each nodule were obtained to be compared between groups

and the efficiency of the specific sonographic signs of MTN for diagnosis of MTN were observed.

Results:

During the follow-up

the size of MTN were significantly decreased (

＜0.05)

and the reduction rate is (714)%. There were statistically significant differences of aspect ratio

calcification morphology

calcification location

blood flow signal

double ring sign

and the enhancement patterns between groups (all

＜0.05)

but not of echogenicity and margin of the nodules between groups (both

＞0.05). The specificity and positive predictive value of no enhancement pattern of CEUS for diagnosing MTN were all 100.00%.

Conclusion:

The contrast of previous ultrasound images and peripheral massive calcification (arc

annulus

eggshell)

double ring sign and no enhancement pattern of CEUS are helpful for the diagnosis of MTN and the efficiency of CEUS for diagnosing MTN was significantly higher.

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