Efficacy and safety of ultrasound-guided percutaneous microwave ablation in patients with symptomatic adenomyosis

DENG Erya; LI Qiuyan; ZHU Jinge; LI Jiaxin; LI Xiaolong; ZHANG Huili; YU Songyuan

doi:10.19732/j.cnki.2096-6210.2023.02.012

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Efficacy and safety of ultrasound-guided percutaneous microwave ablation in patients with symptomatic adenomyosis

更新时间：2025-12-15

- Efficacy and safety of ultrasound-guided percutaneous microwave ablation in patients with symptomatic adenomyosis
- Vol. 32, Issue 2, Pages: 182-188(2023)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2023.02.012
  CLC：
- Published Online：28 April 2023，
  
  Published：28 April 2023
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邓尔雅,李秋燕,朱菁莪,等. 超声引导经皮微波消融治疗症状性子宫腺肌病患者的疗效和安全性[J]. 肿瘤影像学, 2023, 32(2): 182-188 https://doi.

org/10.19732/j.cnki.2096-6210.2023.02.012
邓尔雅,李秋燕,朱菁莪,等. 超声引导经皮微波消融治疗症状性子宫腺肌病患者的疗效和安全性[J]. 肿瘤影像学, 2023, 32(2): 182-188 https://doi. DOI： 10.19732/j.cnki.2096-6210.2023.02.012.

org/10.19732/j.cnki.2096-6210.2023.02.012 DOI：

摘要

目的：

探讨超声引导下经皮微波消融（microwave ablation，MWA）治疗有症状的子宫腺肌病患者的疗效和安全性。

方法：

纳入2020年7月2021年6月接受超声引导下MWA的34例子宫腺肌病患者。在治疗后1、3、6和12个月的随访中对子宫体积、子宫腺肌病体积、痛经评分、月经血量、血红蛋白（hemoglobin，Hb）水平、症状严重程度评分（symptom severity score，SSS）和健康相关生活质量评分（health-related quality of life score，HRQL）量表进行评估。

结果：

中位随访时间为12.00（10.50，12.00）个月。在12个月的随访中，MWA治疗后中位子宫体积从148.45（92.08，215.62）mL减少到87.62（55.90，132.97）mL（

＜0.001），中位腺肌症体积从61.08（31.28，93.38）mL减少到13.33（7.95，43.20）mL（

＜0.001）。视觉模拟评分（visual analog scale，VAS）、Hb水平、月经失血图（pictorial blood loss assessment chart，PBAC）评分均较术前明显改善（

＜0.05）。同时，术后的SSS和HRQL评分较MWA前也显示出差异有统计学意义（

＜0.05）。无严重并发症发生且所有轻微并发症均为自限性。

结论：

MWA是治疗症状性子宫腺肌病的一种有效又安全的选择。超声引导下MWA治疗子宫腺肌病在使子宫体积和病灶体积的减少的同时，能明显有效地改善患者痛经、贫血和月经过多症状。

Abstract

Objective:

To explore the efficacy and safety of ultrasound (US)-guided percutaneous microwave ablation (MWA) in patients with symptomatic adenomyosis.

Methods:

From July 2020 to June 2021

34 patients with symptomatic adenomyosis received US-

guided percutaneous MWA were included in this retrospective study. Uterus volume

adenomyosis volume

dysmenorrhea

menstrual blood volume

hemoglobin (Hb) level

symptom severity score (SSS) and health-related quality of life score (HRQL) were evaluated at 1-

6- and 12-month of follow-up after treatment.

Results:

The median follow-up time was 12.00 (10.50

12.00) months. At the 12-month follow-up

median uterine volume decreased from the baseline volume of 148.45 (92.08

215.62) mL to 87.62 (55.90

132.97) mL (

＜0.001) and median adenomyosis volume decreased from 61.08 (31.28

93.38) mL to 13.33 (7.95

43.20) mL (

＜0.001). The visual analog scale (VAS)

Hb level

and pictorial blood loss assessment chart (PBAC) were significantly improved compared to the preoperative period (

＜0.05). Meanwhile

the postoperative SSS and the HRQL score also showedstatistically difference from those before MWA (

＜0.05). No major complications occurred and all minor complications were self-limiting.

Conclusion:

MWA is an effective and safe alternative for the symptomatic adenomyosis. Patients with adenomyosis treated with US-guided MWA resulted in a reduction in uterine volume and adenomyosis volume while significantly improving the symptoms of dysmenorrhea

anemia and menorrhagia.

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