Application progress of&nbsp;<sup> 68</sup> Ga/ <sup>18 </sup>F labeled PSMA in the diagnosis and treatment of solid tumors other than prostate cancer

ZHANG Zhaoqi; ZHAO Xinming

doi:10.19732/j.cnki.2096-6210.2023.03.002

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Application progress of ⁶⁸ Ga/ ¹⁸F labeled PSMA in the diagnosis and treatment of solid tumors other than prostate cancer

更新时间：2025-12-15

- Application progress of ⁶⁸ Ga/ ¹⁸F labeled PSMA in the diagnosis and treatment of solid tumors other than prostate cancer
- Vol. 32, Issue 3, Pages: 213-225(2023)
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- DOI：10.19732/j.cnki.2096-6210.2023.03.002
  CLC：
- Published Online：28 June 2023，
  
  Published：28 June 2023
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张召奇,赵新明. ⁶⁸Ga/ ¹⁸F标记PSMA在非前列腺癌肿瘤诊疗中的应用进展[J]. 肿瘤影像学, 2023, 32(3): 213-225 https://doi.

org/10.19732/j.cnki.2096-6210.2023.03.002
张召奇,赵新明. ⁶⁸Ga/ ¹⁸F标记PSMA在非前列腺癌肿瘤诊疗中的应用进展[J]. 肿瘤影像学, 2023, 32(3): 213-225 https://doi. DOI： 10.19732/j.cnki.2096-6210.2023.03.002.

org/10.19732/j.cnki.2096-6210.2023.03.002 DOI：

摘要

前列腺特异性膜抗原（prostate-specific membrane antigen，PSMA）最早在前列腺癌细胞中发现，是前列腺癌诊疗的重要靶点。

Ga/

F-PSMA正电子发射体层成像（positron emission tomography，PET）/计算机体层成像（computed tomography，CT）或PET/磁共振成像（magnetic resonance imaging，MRI）在前列腺癌的诊疗中发挥着重要作用。随着研究和应用的不断深入和拓展，研究者发现肝癌、肺癌、肾癌等其他实体肿瘤均摄取

Ga/

F-PSMA，因此，

Ga/

F-PSMAPET/CT在这些肿瘤诊疗中的价值也逐渐体现出来。本文就

Ga/

F-PSMA PET/CT或PET/MRI在非前列腺癌肿瘤诊疗中的应用进行述评。

Abstract

Prostate-specific membrane antigen (PSMA) first discovered in prostate cancer cells is an important target for diagnosis and treatment of prostate cancer.

Ga/

F-PSMA positron emission tomography (PET)/computed tomography (CT) or PET/magnetic resonance imaging (MRI) plays an important role in prostate cancer. With the rapid development of research and application

liver cancer

lung cancer

kidney cancer and other solid tumors can also accumulate

Ga/

F-PSMA reflecting theimporta

nt applications of

Ga/

F-PSMA PET/CT in these tumors. This paper reviewed the application of

Ga/

F-PSMA PET/CT in the diagnosis and treatment of non-prostate cancer tumors.

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Related Institution

Department of Pharmacy, Wuxi Maternal and Child Health Hospital Affiliated to Nanjing Medical University

Wuxi Medical College, Jiangnan University

Department of Pharmacy, Wuxi Maternal and Child Health Care Hospital

Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Center for Biomedical Imaging, Fudan University, Shanghai Engineering Research Center of Molecular Imaging Probes

Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, School of Medicine, Xiamen University

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Application progress of 68 Ga/ 18 F labeled PSMA in the diagnosis and treatment of solid tumors other than prostate cancer

DOI：10.19732/j.cnki.2096-6210.2023.03.002

摘要

Abstract

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Application progress of ⁶⁸ Ga/ ¹⁸F labeled PSMA in the diagnosis and treatment of solid tumors other than prostate cancer