The application value of CEUS time-intensity curve quantitative model in cervical cancer concurrent chemoradiotherapy

TANG Xiuliang; MIAO Qing; YANG Bin nbsp

doi:10.19732/j.cnki.2096-6210.2023.05.006

您当前的位置：

首页 >

文章列表页 >

The application value of CEUS time-intensity curve quantitative model in cervical cancer concurrent chemoradiotherapy

更新时间：2025-12-15

- The application value of CEUS time-intensity curve quantitative model in cervical cancer concurrent chemoradiotherapy
- Vol. 32, Issue 5, Pages: 435-439(2023)
- 作者机构：
  
  1. 江苏省肿瘤医院超声科,江苏,南京,210009
  2. 南京医科大学金陵临床医学院,江苏,南京,210002
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2023.05.006
  CLC：
- Published Online：01 November 2023，
  
  Published：01 November 2023
- 稿件说明：
移动端阅览
唐修亮,缪青,杨斌. CEUS时间-强度曲线定量模型在宫颈癌同步放化疗中的应用价值[J]. 肿瘤影像学, 2023, 32(5): 435-439 https://doi.

org/10.19732/j.cnki.2096-6210.2023.05.006
唐修亮,缪青,杨斌. CEUS时间-强度曲线定量模型在宫颈癌同步放化疗中的应用价值[J]. 肿瘤影像学, 2023, 32(5): 435-439 https://doi. DOI： 10.19732/j.cnki.2096-6210.2023.05.006.

org/10.19732/j.cnki.2096-6210.2023.05.006 DOI：

摘要

目的：

探讨超声造影（contrast-enhanced ultrasound，CEUS）时间-强度曲线（time intensity curve，TIC）定量模型在中晚期宫颈癌患者同步放化疗（concurrent chemoradiotherapy，CCRT）效果评估中的临床价值。

方法：

选取2018年8月—2020年8月于江苏省肿瘤医院放疗科住院接受CCRT治疗的中晚期宫颈癌患者16例，所有患者在接受治疗前、治疗2周和外照射结束后行经阴道CEUS检查，并采用CEUS联合TIC定量模型进行分析。

结果：

整体患者及TP方案组CCRT治疗2周和外照射结束后达峰时间分别较治疗前明显缩短；TP方案组CCRT治疗2周曲线下面积较治疗前明显增加。

结论：

CEUS联合TIC能够体现中晚期宫颈癌CCRT治疗后肿瘤内部血流灌注变化情况，具有一定的早期疗效评估价值。

Abstract

Objective:

To investigate the clinical value of the quantitative model of contrast-enhanced ultrasound (CEUS) time- intensity curve (TIC) in the evaluation of the therapeutic efficacy during concurrent chemoradiotherapy (CCRT) for advanced cervical cancer.

Methods:

Sixteen patients with advanced cervical cancer who received CCRT in the Department of Radiation Oncology at Jiangsu Cancer Hospital from August 2018 to August 2020 were selected. All patients underwent transvaginal CEUS before treatment

at 2 weeks of treatment

and after completion of external irradiation. CEUS combin

ed with TIC quantitative analysis was conducted.

Results:

Both the overall patient group and TP group showed significantly shortened time to peak enhancement at 2 weeks into CCRT treatment and after external irradiation compared to before treatment. The TP group exhibited a significant increase in the area under the curve at 2 weeks into treatment compared to before treatment.

Conclusion:

The combined use of CEUS and TIC analysis can reflect changes in tumor perfusion after CCRT treatment for advanced cervical cancer

providing a certain value in early therapeutic efficacy assessment.

关键词

Keywords

references

Views

465

下载量

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Prediction of outcomes in patients with locally advanced cervical cancer after concurrent chemoradiotherapy based on machine learning-based radiomics

Primary study on perfusion-weighted imaging in concurrent chemoradiotherapy of cervical cancer

A preliminary study on the application of Sonazoid contrast-enhanced ultrasound in improving the detection rate of liver nodules

Research on a prediction model for superficial lymphoma based on multimodal ultrasound radiomics

Contrast-enhanced ultrasound findings of gallbladder adenosquamous carcinoma: a case report

Related Author

Meng LI

Shisheng XU

Jiehui Li

WANG Xiaoyu

WANG Yue

YU Tao

LUO Yahong

WU Yi

Related Institution

Department of Oncology, Affiliated Hospital of Guizhou Medical University

Department of Oncology, Guizhou Medical University Affiliated Cancer Hospital

Division of Oncology Teaching and Research, School of Clinical Medicine, Guizhou Medical University

Department of Oncology, Qingdao Municipal Hospital

Department of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University

AI问答

⁰