Diagnostic value of next generation sequencing combined with CT in pulmonary infection of hematological malignancies&nbsp;

YANG Xiao; GUO Guiying; SUN Jiannan

doi:10.19732/j.cnki.2096-6210.2023.05.011

您当前的位置：

首页 >

文章列表页 >

Diagnostic value of next generation sequencing combined with CT in pulmonary infection of hematological malignancies

更新时间：2025-12-15

- Diagnostic value of next generation sequencing combined with CT in pulmonary infection of hematological malignancies
- Vol. 32, Issue 5, Pages: 466-471(2023)
- 作者机构：
  
  1. 哈尔滨医科大学附属第六医院影像中心，黑龙江哈尔滨 ,150023
  2. 哈尔滨市第一医院血液肿瘤研究中心，黑龙江哈尔滨 ,150000
  3. 大庆油田总医院 CT 室，黑龙江大庆 ,163000
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2023.05.011
  CLC：
- Published Online：03 November 2023，
  
  Published：03 November 2023
- 稿件说明：
移动端阅览
杨　潇,郭桂英,孙建男. 二代测序技术联合CT在恶性血液病肺部感染中的诊断价值肿瘤影像学, 2023, 32(5): 466-471 https://doi.

org/10.19732/j.cnki.2096-6210.2023.05.011
杨　潇,郭桂英,孙建男. 二代测序技术联合CT在恶性血液病肺部感染中的诊断价值肿瘤影像学, 2023, 32(5): 466-471 https://doi. DOI： 10.19732/j.cnki.2096-6210.2023.05.011.

org/10.19732/j.cnki.2096-6210.2023.05.011 DOI：

摘要

恶性血液病（hematologic malignancies，HM）肺部感染是临床常见且频发的疾病，早期、准确并快速确定病原体类型是治疗的关键，传统检测手段具有一定可靠性但存在许多不足。近年来，随着宏基因组二代测序技术（metagnomic next generation sequencing，mNGS）逐步应用于临床，病原mNGS在肺部感染病变的诊断中体现出一定价值，HM在不同的阶段出现各种肺部感染往往具有一定的临床特点及计算机体层成像（computed tomography，CT）影像学表现。本文聚焦于mNGS及CT两种检查手段，对其各自特点及HM肺部感染的联合诊断现状进行综述。

Abstract

Pulmonary infection in hematological malignancies (HM) is one of the common and frequent diseases in clinical practice. Early

accurate and rapid determination of pathogen types is the key to treatment. The traditional detection methods have certain reliability but present many shortcomings. In recent years

with the continuous development of metagenomic next generation (mNGS) technology in clinical practice

the application of mNGS of pathogens in the diagnosis of pulmonary infection lesions reflects a certain value

and HM often has certain clinical and computed tomography (CT) imaging characteristics in different stages of various pulmonary infections. This article focused on mNGS and CT examination methods

and reviewed and analyzed their respective characteristics and the current status of the diagnosis of HM pulmonary infection.

关键词

Keywords

references

Views

457

下载量

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Multi-region radiomics features from enhanced CT combined with clinical risk factors for preoperative prediction of lymphovascular invasion in colon cancer

Application value of multimodal imaging technology based on CT and MRI in the diagnosis and PRETEXT staging of childhood hepatoblastoma

The predictive value of CT radiomics model for immunotherapy efficacy in non-small cell lung cancer

One case: chondromyxoid fibroma of the rib in children

Preliminary study on the identification of benign and malignant lung nodules and prediction of pathological types using artificial intelligence software based on CT target scan

Related Author

Wanping LI

Wenbin ZHENG

Liya LU

Xiao YU

Yanan LI

Qiancheng LI

Tao XIN

Chenglong LI

Related Institution

Department of Radiology, The Second Affiliated Hospital of Shantou University Medical College

Department of Radiology, Puning People's Hospital, Puning

Shantou University Medical School

Department of Imaging, Xuzhou Children's Hospital

Department of Radiology, Huadong Hospital, Fudan University

AI问答

⁰