Diagnostic value of conventional ultrasound combined with contrast-enhanced ultrasound in cystic solid thyroid nodule

PAN Dai; XU Yuanbing; TAO Yichao; MA Fen; WU Xiaofeng; XIAO Lan; YANG Fei; HU Cong

doi:10.19732/j.cnki.2096-6210.2024.03.009

您当前的位置：

首页 >

文章列表页 >

Diagnostic value of conventional ultrasound combined with contrast-enhanced ultrasound in cystic solid thyroid nodule

更新时间：2025-12-15

- Diagnostic value of conventional ultrasound combined with contrast-enhanced ultrasound in cystic solid thyroid nodule
- Vol. 33, Issue 3, Pages: 270-275(2024)
- 作者机构：
  
  1. 武汉科技大学附属孝感医院超声科,湖北,孝感,432000
  2. 武汉科技大学附属孝感医院甲乳外科,湖北,孝感,432000
  3. 武汉科技大学附属孝感医院病理科,湖北,孝感,432000
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2024.03.009
  CLC：
- Published Online：17 July 2024，
  
  Published：17 July 2024
- 稿件说明：
移动端阅览
潘代,徐元兵,陶溢潮,等. 常规超声联合超声造影对甲状腺部分囊性结节的诊断价值[J]. 肿瘤影像学, 2024, 33(3): 270-275 https://doi.

org/10.19732/j.cnki.2096-6210.2024.03.009
潘代,徐元兵,陶溢潮,等. 常规超声联合超声造影对甲状腺部分囊性结节的诊断价值[J]. 肿瘤影像学, 2024, 33(3): 270-275 https://doi. DOI： 10.19732/j.cnki.2096-6210.2024.03.009.

org/10.19732/j.cnki.2096-6210.2024.03.009 DOI：

摘要

目的：

探讨常规超声联合超声造影对甲状腺部分囊性结节（partially cystic thyroid nodule，PCTN）的诊断价值。

方法：

回顾并分析2018年1月—2022年8月经超声检出为PCTN并经细针穿刺或术后病理学检查确诊的252例患者的资料。所有患者为单发结节，术前均接受超声造影检查。以病理学检查结果为金标准，绘制受试者工作特征（receiver operating characteristic，ROC）曲线，比较超声造影、常规超声及两者联合的诊断效能。

结果：

252个结节中良性结节189个，恶性结节63个，常规超声、超声造影诊断PCTN的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为82.0%、88.9%、84.1%、95.7%、62.2%和89.9%、85.7%、88.9%、94.9%、73.9%，曲线下面积（area under curve，AUC）分别为0.854、0.878。联合诊断后灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为95.8%、84.1%、92.9%、94.8%、86.9%，AUC为0.899，明显高于单一的诊断方式（

＜0.05）。

结论：

常规超声及超声造影对PCTN具有较高的诊断效能，两者联合应用能提高诊断灵敏度、准确度、阴性预测值，有助于指导PCTN的治疗与管理。

Abstract

Objective:

To investigate the diagnostic value of conventional ultrasound combined with contrast-enhanced ultrasound in the diagnosis of partially cystic thyroid nodule (PCTN).

Methods:

A retrospective analysis was performed on 252 patients with PCTN detected by ultrasound and pathological results obtained by fine-needle puncture or surgical operation from January 2018 to August 2022. Al

l patients were single nodules. All patients underwent contrast-enhanced ultrasound examination before surgery. With pathological results as the gold standard

receiver operating characteristic (ROC) curve was drawn to compare the diagnostic efficacy of contrast-enhanced ultrasound

conventional ultrasound and conventional ultrasound combined with contrast-enhanced ultrasound.

Results:

Of the 252 nodules

189 were benign and 63 were malignant. The sensitivity

specificity

accuracy

positive predictive value and negative predictive value of conventional ultrasound and contrast-enhanced ultrasound in the diagnosis of PCTN were 82.0%

88.9%

84.1%

95.7%

62.2% and 89.9%

85.7%

88.9%

94.9%

73.9%

respectively. The area under curve (AUC) was 0.854 and 0.878

respectively. After combined diagnosis

the sensitivity

specificity

accuracy

positive predictive value and negative predictive value were 95.8%

84.1%

92.9%

94.8% and 86.9%

respectively

and the AUC was 0.899

which significantly higher than the single diagnostic method (

＜0.05).

Conclusion:

Conventional ultrasound and contrast-enhanced ultrasound have high diagnostic efficacy for PCTN

and the combined application of the two can improve the diagnostic sensitivity

accuracy and negative predictive value

which is helpful to guide the treatment and management of PCTN.

关键词

Keywords

references

Views

289

下载量

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Diagnostic value of contrast-enhanced ultrasound combined with fine-needle aspiration biopsy in thyroid TI-RADS 4 nodules

A preliminary study on the application of Sonazoid contrast-enhanced ultrasound in improving the detection rate of liver nodules

Multivariate analysis of ultrasonographic characteristics for differentiating benign and malignant BethesdaⅢ category thyroid nodules

Contrast-enhanced ultrasound findings of gallbladder adenosquamous carcinoma: a case report

LI-RADS analysis and differential diagnosis of intrahepatic cholangiocarcinoma by contrast-enhanced ultrasound

Related Author

Weijuan FAN

Tongtong ZHAO

Huan ZHANG

Yaping HE

Xiangliu OUYANG

WU Yi

HUANG Tianjiao

WEN Baojie

Related Institution

Department of Ultrasound, Tangshan Central Hospital

North China University of Science and Technology

Department of Ultrasound, Tangshan Gongren Hospital

Department of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University

Department of Ultrasound, The Fourth Affiliated Hospital of Nanjing Medical University

AI问答

⁰