The efficacy and safety of  <sup>177</sup>Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study

Xinyi LIN; Wei WANG; Tingting XU; Lin QIU; Jian YANG; Lixian MOU; Chunyin ZHANG; Yue CHEN

doi:10.19732/j.cnki.2096-6210.2025.05.006

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The efficacy and safety of ¹⁷⁷Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study

更新时间：2025-12-15

- The efficacy and safety of ¹⁷⁷Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study
- “A study conducted by the Affiliated Hospital of Southwest Medical University shows that 177Lu DOTA-IBA has a significant therapeutic effect on lung cancer bone metastasis, with a pain relief rate of 82.2%, a physical improvement rate of 64.4%, and good safety.”
- Oncoradiology Vol. 34, Issue 5, Pages: 477-486(2025)
- 作者机构：
  
  1. 西南医科大学附属医院核医学科，四川泸州 646000
  2. 核医学诊疗四川省重点实验室，四川泸州 646000
  3. 西南医科大学核医学研究所，四川泸州 646000
  4. 靶向放射性药物创制四川省重点实验室，四川泸州 646000
- 作者简介：
- 基金信息：
  
  National Natural Science Foundation of China (NSFC)(82472016);Gansu Province Science and Technology Major Project(23ZDFA014);Isotope and Drug Innovation Fund of the National Engineering Research Center for Isotopes and Drugs(TWSCX-2023-CXJJ-3-1);Science and Technology Department of Sichuan Province(2024YFCY0005)
- DOI：10.19732/j.cnki.2096-6210.2025.05.006
  CLC：
- Received：15 September 2025，
  
  Published Online：06 November 2025，
  
  Published：28 October 2025
- 稿件说明：
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Xinyi LIN, Wei WANG, Tingting XU, et al. The efficacy and safety of ¹⁷⁷Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study[J]. Oncoradiology, 2025, 34(5): 477-486.
DOI：

Xinyi LIN, Wei WANG, Tingting XU, et al. The efficacy and safety of ¹⁷⁷Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study[J]. Oncoradiology, 2025, 34(5): 477-486. DOI： 10.19732/j.cnki.2096-6210.2025.05.006.

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Related Institution

Department of Nuclear Medicine, Affilitated Hospital of Southwest Medical University

Department of Nuclear Medicine, Chengdu Seventh People’s Hospital, Affilitated Cancer Hospital of Chengdu Medical College

Department of Radiology, Chengdu Seventh People’s Hospital, Affilitated Cancer Hospital of Chengdu Medical College

Philips Clinical & Technical Support Department

Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University

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The efficacy and safety of 177Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study

DOI：10.19732/j.cnki.2096-6210.2025.05.006

The efficacy and safety of ¹⁷⁷Lu-DOTA-IBA in the treatment of bone metastases from lung cancer: a prospective single-arm study