Interpretation of the NCCN guidelines for non-small cell lung cancer (version 3, 2026) and practical recommendations for radiology

FAN Rongrong; WANG Yun; XIAO Yi

doi:10.19732/j.cnki.2096-6210.2026.02.014

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Interpretation of the NCCN guidelines for non-small cell lung cancer (version 3, 2026) and practical recommendations for radiology

Guidelines and Standards | 更新时间：2026-05-07

- Interpretation of the NCCN guidelines for non-small cell lung cancer (version 3, 2026) and practical recommendations for radiology
- Oncoradiology Vol. 35, Issue 2, Pages: 330-340(2026)
- 作者机构：
  
  海军军医大学第二附属医院放射诊断科，上海 200003
- 作者简介：
- 基金信息：
  
  Shanghai Shenkang Hospital Development Center Diagnosis and Treatment Technology Promotion and Optimization Management Project(SHDC22025311-A)
- DOI：10.19732/j.cnki.2096-6210.2026.02.014
  CLC： R734.2;R445
- Received：30 March 2026，
  
  Revised：2026-04-14，
  
  Accepted：14 April 2026，
  
  Published：28 April 2026
- 稿件说明：
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樊荣荣, 望　云, 萧　毅. NCCN 2026年V3版非小细胞肺癌指南解读与影像科实践建议［J］. 肿瘤影像学, 2026, 35(2): 330-340.

FAN R　R, WANG Y, XIAO YCitation:. Interpretation of the NCCN guidelines for non-small cell lung cancer (version 3, 2026) and practical recommendations for radiology［J］. Oncoradiology, 2026, 35(2): 330-340.
樊荣荣, 望　云, 萧　毅. NCCN 2026年V3版非小细胞肺癌指南解读与影像科实践建议［J］. 肿瘤影像学, 2026, 35(2): 330-340. DOI： 10.19732/j.cnki.2096-6210.2026.02.014.

FAN R　R, WANG Y, XIAO YCitation:. Interpretation of the NCCN guidelines for non-small cell lung cancer (version 3, 2026) and practical recommendations for radiology［J］. Oncoradiology, 2026, 35(2): 330-340. DOI： 10.19732/j.cnki.2096-6210.2026.02.014.

摘要

中国的肺癌发病率与死亡率均居各类癌症之首，给医疗行业带来巨大挑战。非小细胞肺癌（non-small cell lung cancer，NSCLC）约占肺癌总病例数的85%，是全球范围内恶性肿瘤相关死亡的首要原因。美国国立综合癌症网络（National Comprehensive Cancer Network，NCCN）NSCLC临床实践指南（2026年V3版）作为全球肺癌诊疗的权威参考标准，更新了TNM分期体系，优化了肺癌筛查、诊断、分期、治疗监测及复发评估全流程的影像学相关内容，新增多项贴合临床实际的评估规范与特殊场景处理建议。本文旨在解读NCCN 2026年V3版NSCLC指南中与影像学密切相关的内容，并为影像科医师的临床实践、报告规范及多学科协作提供系统性建议。

Abstract

Lung cancer ranks first in both incidence and mortality among all malignant neoplasms in China

presenting a substantial challenge to the healthcare system. Non-small cell lung cancer (NSCLC) constitutes approximately 85% of all lung cancer cases and represents the leading cause of cancer-related mortality worldwide. As a globally authoritative benchmark for the diagnosis and management of lung cancer

the National Comprehensive Cancer Network (NCCN) clinical practice guidelines in oncology: NSCLC (version 3.2026) issued by the NCCN has updated the TNM staging system

refined imaging-related components throughout the entire continuum of lung cancer screening

diagnosis

staging

treatment response monitoring

and recurrence assessment

and incorporated multiple clinically oriented evaluation criteria and recommendations for the management of specific clinical scenarios. This article sought to interpret the imaging-relevant sections of the 2026 version 3 NCCN NSCLC guidelines and provide systematic guidance for clinical practice

standardized reporting

and multidisciplinary collaboration among radiologists.

关键词

Keywords

references

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