Objective:

To investigate the ultrasonographic characteristics of uveal metastatic carcinoma.

Methods:

The data of 29 eyes of 25 patients diagnosed of uveal metastatic carcinoma from January 2012 to November 2016 were retrospectively analyzed. The B-mode ultrasonography and color Doppler flow imaging (CDFI) were performed on them. Contrast-enhancedultrasound was performed on 14 cases (14 eyes)

and the characteristics of the time-intensity curve of the

contrast agent were analyzed.

Results:

Among 25 cases (29 eyes) of uveal metastatic carcinoma

left eye was involved in 8 cases (32.0%)

right eye was involved in 13 cases (52.0%) and both eyes were involved in 4 cases (16.0%). Four eyes (13.8%) located in the iris ciliary body and 25 eyes (86.2%) in the choroid. Ultrasound showed flat echo lesion in 7 eyes (24.1%)

hemispherical echo in 7 eyes (24.1%)

and irregular surface of notch or wavy in 15 eyes (51.7%). The mean height of the lesions was (3.52.2) mm

and the mean baseheight ratio was 3.72.1. In 27 eyes (93.1%) the echo of the lesions was lower than that of the adjacent orbital tissues. Two eyes (6.9%) showed hollowing out

and 5 eyes (17.2%) showed choroidal excavation. Secondary retinal detachment occurred in 21 eyes (72.4%)

and vitreous opacity in 11 eyes (38.0%). CDFI examination showed branch-shaped blood flow signal in 21 eyes (72.4%). The time-intensity curve in 13 eyes (92.9%) showed quick in and quick out.

Conclusion:

Uveal metastatic carcinoma has certain ultrasonographic characteristics

which can provide a reliable basis for clinical diagnosis and differential diagnosis.