Objective:

To investigate the value of

131

I imaging

thyroglobulin (Tg) value and chest CT in the assessment of

131

I therapy in patients with lung metastases from differentiated thyroid carcinoma (DTC).

Methods:

From June 2008 to June 2014

42 patients with lung metastases from DTC were retrospectively analyzed.

131

I imaging

Tg value

and chest CT were carried out in the assessment of diagnosis and follow-up.

Results:

59.5% (25/42) cases achieved a response by

131

I therapy

while 40.5% (17/42) cases had no effective response. The effective rates of treatment assessed by single

131

I imaging

chest CT and Tg value were 64.3% (27/42)

71.4% (30/42) and 59.5% (25/42). There was significant difference in Tg value before and after

131

I therapy (

Z

=- 2.026

P

=0.043).

Conclusion:

131

I therapy is effective in treatment and control DTC lung metastases in most patients. An obviously increased Tg value demonstrates a poor prognosis.

131

I imaging

chest CT and Tg value are important procedures in the assessment of

131

I therapy in patients with lung metastases from DTC.