Objective:

To compare the elasticity changes between diabetic nephropathy and hypertensive renal disease in the uremia stage，and measure the thickness of the renal cortex to analyze its relationship with elastic index (EI) of the cortex.

Methods:

A total of 38 uremia patients were divided into two groups: diabetic nephropathy group (

n

=20) and hypertensive renal disease group (

n

=18). Independent-samples t test was used to compare EI values in the cortex

medulla and sinu between the two groups. The correlation between the thickness of the cortex and EI v

alue of the cortex was investigated.

Results:

In the cortex

EI value in the diabetic nephropathy group was higher than that in the hypertensive renal disease group (

t

＝-2.37

P

0.05); while in the medulla

EI value in the diabetic nephropathy group was lower than that in the hypertensive renal disease group (

t

＝2.43

P

0.05). There was no significant difference in EI value in the sinu between the two groups (

t

＝0.55

P

0.05). There was no significant difference in the thickness of the cortex between the two groups (

t

＝-1.01

P

0.05) . The thickness of the cortex was correlated with EI value (

r

＝0.35

P

0.05).

Conclusion:

In the uremia stage

there are different changes in renal elasticity between diabetic nephropathy and hypertensive renal disease. Cortical EI value is positively correlated with its thickness.