To explore the relationship between ultrasound radiomics features and invasive proteins in metastasis of papillary thyroid carcinoma (PTC).
Methods:
Thirty cases of PTC in Fudan University Shanghai Cancer Center were selected. Ultrasound radiomics prediction system was used to predict lymph node metastasis. All lesion tissues were analyzed by protein spectrum and screened to obtain invasive proteins. The correlation between radiomics features with protein expressions was analyzed by Pearson correlation coefficient.
Results:
The accuracy of lymph node metastasis predicted by radiomics was 96.7%. There were 4 proteins extremely strongly correlated with 19 radiomics features
5 proteins strongly correlated with 23 radiomics features.
Conclusion:
There is a correlation between ultrasound radiomics features with invasive proteins in lymph node metastasis of PTC.