To discuss the imaging characteristics of triple-negative breast cancer (TNBC) and to compare the results with characteristics of non-TNBC (NTNBC).
Methods:
Forty-two cases with TNBC and 504 cases with NTNBC confirmed by pathology and immunohistochemistry were retrospectively analyzed. Mammography and MRI were performed. The calcification
shape
edge
T2 signal
enhancement pattern and time-intensity curve (TIC) between the two groups were compared by c
hi-square test.
Results:
On mammography
TNBC usually presented with a round (10/25
40%) mass with less calcifications (17/28
61%)
and clear margins (12/25
48%). On MRI
the TNBC usually presented with a round (22/27
82%) mass with clear margins (11/27
41%)
high signal intensity on T2-weighted image (5/27
18.5%)
rim enhancement (8/27
29.6%) and type Ⅲ TIC (20/32
63%). There were statistically significant differences in calcification
edge on mammography between the two groups (
P
0.05). There were statistically significant differences in shape
edge
enhancement pattern
apparent diffusion coefficient (ADC) and TIC on MRI between the two groups (
P
0.05).
Conclusion:
On MRI
the TNBC usually presented with clear margins
rim enhancement
type Ⅲ TIC and a higher ADC. MRI combined with mammography findings has a certain value.