声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值

刘淼; 沈燕; 傅晓红; 吴墅; 何洁

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声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值

论著 | 更新时间：2025-12-15

- 声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值
- Diagnostic value of acoustic radiation force impulse imaging in thyroid nodules of TI-RADS 4 category
- 肿瘤影像学 2018年27卷第1期页码：17-22
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- 网络出版：2018-04-03，
  
  纸质出版：2018-04-03
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刘淼, 沈燕, 傅晓红, 等. 声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值[J]. 肿瘤影像学, 2018,27(1):17-22.

刘淼,沈燕,傅晓红,等. 声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值[J]. 肿瘤影像学, 2018, 27(1): 17-22
刘淼, 沈燕, 傅晓红, 等. 声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值[J]. 肿瘤影像学, 2018,27(1):17-22. DOI：

刘淼,沈燕,傅晓红,等. 声脉冲辐射力成像技术在甲状腺TI-RADS 4类结节中的诊断价值[J]. 肿瘤影像学, 2018, 27(1): 17-22 DOI：

摘要

目的

探讨声触诊组织成像和定量（virtual touch tissue imaging quantification，VTIQ)技术在不同直径甲状腺影像报告和数据系统（Thyroid Imaging Reporting and Data System，TI-RADS) 4类结节中的诊断价值，并与声触诊组织成像（virtual touch tissue imaging，VTI)技术比较。

方法

回顾性分析经病理证实的201个甲状腺TI-RADS 4类结节的VTIQ和VTI图像资料。甲状腺TI-RADS 4类结节按不同直径（10 mm和10 mm)分成两组，VTIQ以剪切波速度（shear wave velocity，SWV)表示，评价VTIQ、VTI及两者联合诊断甲状腺癌的灵敏度、特异度和准确率。以病理结果为金标准，绘制受试者工作特性（receiver operating characteristic，ROC)曲线，进行曲线下面积（area under curve，AUC)比较。

结果

197例患者201个结节中，恶性结节104个，良性结节97个。结节直径10 mm者95个，VTI、VTIQ及两者联合诊断甲状腺癌的灵敏度、特异度、准确率、AUC分别为81.25%、80.85%、81.05%、0.811，87.50%、78.72%、83.16%、0.831，95.83%、78.72%、87.37%、0.873。结节直径10 mm者106个，VTI、VTIQ及两者联合诊断甲状腺癌的灵敏度、特异度、准确率、AUC分别为83.93%、72.00%、78.30%、0.780，76.79%、78.00%、77.36%、0.774，96.43%、60.00%、79.25%、0.782。结节直径10 mm组中VTI和VTIQ两者联合诊断优于各自单独诊断，差异有统计学意义（

0.05)。结节直径10 mm组VTI和VTIQ两者联合诊断具有优势，差异有统计学意义（

0.05)。

结论

VTI、VTIQ及两者联合对不同直径的甲状腺结节均有诊断价值，声脉冲辐射力成像技术可作为常规超声诊断甲状腺结节的重要辅助手段。VTI和VTIQ联合诊断直径10 mm的结节优于各自单独诊断，随着结节增大，两者联合诊断效能降低。

Abstract

Objective

　To evaluate the diagnostic value of virtual touch tissue imaging quantification (VTIQ) in iden

tifying thyroid nodules of Thyroid Imaging Reporting and Data System (TI-RADS) 4 category

and compare with virtual touch tissue imaging (VTI).

Methods

　The features of VTIQ and VTI images of 201 thyroid nodules of TIRADS 4 category

which were diagnosed based on pathological examination

were retrospectively analyzed. They were divided into two groups according to diameter (10 mm and 10 mm). VTIQ was expressed as shear wave velocity (SWV). The sensitivity

specificity and accuracy of VTIQ and VTI diagnosing thyroid carcinoma were evaluated. Receiver operating characteristic (ROC) curve was used to compare the area under the curve (AUC) between the two groups.

Results

　In 201 thyroid nodules

there were 104 malignant nodules and 97 benign nodules. In the group of diameter 10 mm

the sensitivity

specificity

accuracy and AUC of VTIQ

VTI and their combination were 81.25%

80.85%

81.05%

0.811; 87.50%

78.72%

83.16%

0.831; and 95.83%

78.72%

87.37%

0.873

respectively. In the group of diameter 10 mm

the sensitivity

specificity

accuracy and AUC of VTIQ

VTI and their combination were 83.93%

72.00%

78.30%

0.780; 76.79%

78.00%

77.36%

0.774; and 96.43%

60.00%

79.25%

0.782

respectively.The diagnostic value of combination of VTIQ and VTI in nodules with diameter 10 mm was superior to the single method alone (

0.05). The diagnostic value of combination of VTIQ and VTI in nodules of TI-RADS 4 category with diameter10 mm is superior to other methods (

0.05).

Conclusion:

VTI

VTIQ and their combination in diagnosing thyroid carcinoma with different diameters can be used as an important adjunct to conventional ultrasound. The combination of VTI and VTIQ in diagnosing nodules with diameter10 mm is better than single method alone.

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