对49例子宫肌瘤患者在HIFU治疗前、治疗后进行CEUS及MRI检查,对患者的临床资料、检查结果及疗效进行分析。术前分析患者年龄,靶皮距,肌瘤位置、类型、体积,CEUS达峰时间(time to peak,TTP)、达峰强度(peak intensity,PI)、增强形态,MRI T2WI信号强度及增强程度,术后评估病灶消融率。
To explore the contrast-enhanced ultrasound (CEUS) and MRI factors influencing the therapeutic effects of high intensify focused ultrasound (HIFU) in the treatment of hysteromyoma.
Methods:
Forty-nine patients with hysteromyoma were examined by CEUS and MRI before and after HIFU treatment. The data of patients age
target-skin distance
hysteromyoma location
type
volume
time to peak (TTP)
peak intensity
enhanced morphology of CEUS
signal intensity of preexisting T2-weighted and enhancement degree of MR images were analyzed respecti
vely. After HIFU treatment
non-perfused volume (NPV) was observed.
Results:
After HIFU treatment
35 cases had NPV ratio 70%
and 14 cases had NPV ratio 70%. Logistic analysis showed that TTP
peak intensity
signal intensity of preexisting T2-weighted and enhancement degree of MR images were associated with HIFU efficiency (
P
0.05).
Conclusion:
TTP
peak intensity
signal intensity of preexisting T2-weighted and enhancement degree of MR images could affect HIFU efficiency in the treatment of hysteromyoma
and may be used to predict the therapeutic effects of HIFU.