Objective:

To investigate the radiologic and pathologic characteristics of solitary fibrous tumor of the pleura (SFTP).

Methods:

A total of 15 cases of SFTP confirmed by surgery and pathology were retrospectively analyzed. Thirteen cases underwent plain and enhanced CT scanning (one underwent MRI scanning at the same time)

and 2 cases underwent MRI scanning only. The location

size

shape

density or signal intensity and enhancement pattern of the tumors were studied.

Results:

All the 15 cases presented solitary masses with well-defined margin

among whi

ch 10 were round or oval-like and 5 were lobulated. Most of the masses showed iso-attenuation on plain CT with homogeneous or heterogeneous density

and 2 with calcification. Iso- or hypointense on T1WI

Iso- or hyperintense on T2WI

hyperintense on diffusion weighted imaging (DWI) were shown. After the administration of contrast agent

all of the tumors presented gradually delayed enhancement pattern. Six tumors manifested obvious enhancement

9 tumors showed mild or moderate enhancement

and 6 tumors had affluent tumor vessel. Four cases showed pleura tail sign

and 12 cases showed that surrounding lung tissues were pushed to form a strip with high density. Microscopically

these tumors consisted of whorls of reticulin and collagen with interspersed spindle-shaped cells

without significant nuclear division. Immunohistochemical analysis showed that Vimentin (+) (7/8)

CD34 (+) (8/8)

Bcl-2 (+) (5/8).

Conclusion:

SFTP can be expressed as an isolated mass with well-defined margin

lager size and delayed enhancement pattern after enhancement

which can be used as clinical evidence for its diagnosis.