Evaluating the clinical value of IOTA Logistic regression model LR2 in predicting benign and malignant ovarian tumors by ultrasound.
Methods:
This study selected the patients who had been hospitalized surgical treatment in the Third Affiliated Hospital of Zhengzhou University due to the adnexal tumors
all the patients underwent ultrasound
observed and summarized the image
then used IOTA post-processing software calculating the
risk index
follow-up postoperative pathological results
analyzed the sensitivity
specificity
positive predictive value
negative predictive value
positive likelihood ratio
negative likelihood ratio and the area under curve (AUC) of the receiver operating characteristic (ROC).
Results:
A total of 215 patients were calculated
including 126 benign tumors (58.6%) and 89 malignant tumors(41.4%)
the sensitivity was 95.5% (95%CI: 90.4%-98.3%)
the specificity was 76.2% (95%CI: 62.7%-87.7%)
the AUC was 0.89 (SE=0.024
95%CI: 0.87-0.91).
Conclusion:
IOTA Logistic regression model LR2 has highly diagnosis value in evaluating the ovarian tumors
which can be used as an auxiliary diagnosis method for non-gynecological ultrasound or non-expert operators.