Molecular imaging can be used to non-invasively detect physiological changes in the body

which is conducive to the study of disease etiology

occurrence

development and outcome. In recent years

due to the rapid development of micro-nano technology

ultrasound molecular imaging has made considerable progress. Micro-nano materials have unique advantages

can load a variety of drugs/molecules

is easy for physical and chemical modification

and can be used for multiple targeted transportation

etc. Combined with ultrasound micro-nano materials can lead to the opening of blood brain barrier (BBB)

multimodal imaging

integration of diagnosis and treatment

monitoring of tumor microenvironment markers and signal amplification. Further researchshould focus on the research of biosafety

so as to realize the material's non-potential pathogenic toxicity

non-off-target effect

and

in vivo

metabolism. Solving these problems will provide a new diagnosis and treatment model for diseases.