Objective:

To study the value of contrast-enhanced and conventional ultrasound in differential diagnosis of breast phyllodes tumors and fibroadenomas.

Methods:

A retrospective analysis was performed in 80 cases which were pathologically confirmed (23 cases with phyllodes tumors

57 cases with fibroadenomas).

Results:

There was no significant difference in tumors' size

boundary

aspect ratio

calcifications or posterior echo (

P

0.05)

while there were significant differences in age

tumors' shape

wh

ether slit-shaped anechoic area or not

whether hyperechoic intervals or not

vascularization grade

degrees and homogeneities of contrast enhancement (

P

0.05) between breast phyllodes tumors and fibroadenomas. The breast phyllodes tumors were characterized on ultrasound by clear boundary

aspect ratio 1

rare calcifications

posterior echo enhancement

lobulated

abundant flow

slitshaped anechoic area and hyperechoic intervals

which were more common than fibroadenomas. On contrast-enhanced ultrasound phyllodes tumors were characterized by heterogeneously hypo- or iso-enhancement

while fibroadenomas showed homogeneously hyper-enhancement.

Conclusion:

Contrast-enhanced ultrasound and conventional ultrasound have a certain value in the differential diagnosis of breast phyllodes tumors and fibroadenomas

which might provide a helpful reference for the selection of surgical methods.