Objective:

To evaluate the clinical value of combined application of contrast pulse sequencing (CPS) and contrast high resolution imaging (CHI) in the detection of liver metastases.

Methods:

A total of 45 cases of liver metastases were enrolled from Jul. 2017 to Oct. 2018 in Zhongshan Hospital

Fudan Univ

ersity. All lesions were confirmed by pathological results. Combination of CPS and CHI was applied in each patient. Conventional ultrasound was used to detect the lesion echo

number

size

location.

Results:

Among 45 patients of liver metastasis

there were 12 with single lesion

14 with two lesions

and 19 with multiple lesions (3). Conventional ultrasound detected 94 lesions. CPS detected 109 lesions including 82 with peripheral rim-like hyperenhancement and 27 with whole homogenous hyper-enhancement. During portal phase

11 lesions showed slightly peripheral rimlike hyper-enhancement

13 lesions showed slightly homogeneous hyper-enhancement

and 85 lesions showed homogeneous hypoenhancement. During delayed phase

CHI detected more 52 lesions. Totally 161 lesions (

P

＜0.05) showed hypo-enhancement.

Conclusion:

CPS with better contrast and resolution could help to determine the lesions and make more precise diagnosis. CHI with long delayed phase and detailed and high resolution could help to detect more liver metastases. Combined application of CPS andCHI provides vital information in preoperative detection of liver metastases.