Objective:

To evaluate the value of conventional ultrasound combined with contrast-enhanced ultrasound (CEUS) in the diagnosis of triple negative breast cancer (TNBC).

Methods:

Eighty cases of patients with breast cancer were analyzed retrospectively. According to the immunohistochemical results postoperatively

atients were divided into TNBC group and non-TNBC group. Subsequently

the characteristics of the two groups in conventional ultrasound an

d CEUS were analyzed.

Results:

Firstly

there were statistically significant differences between TNBC and non-TNBC in the boundary

morphology and orientation of nodules in conventional ultrasound images (

P

0.05). Most lesions in TNBC appeared as smooth boundary

irregular morphology

and parallel to the skin. However

non-TNBC appeared as burr or crab-footed boundary

irregular morphology

and not parallel to the skin. Secondly

degree of edge enhancement

boundary enhancement

morphology enhancement

the distribution of contrast agents

and whether the lesion was significantly enlarged before and after CEUS were significantly different between the two groups (

P

0.05). Following CEUS

most lesions in TNBC appeared as internal heterogeneous enhancement

high enhancement edge

clear boundary

irregular morphology

and no significant increase before and after CEUS. Non-TNBC appeared as unclear boundary

irregular morphology

and significant increase before and after CEUS.

Conclusion:

The characteristics in CEUS such as degree of edge enhancement

boundary enhancement

morphology enhancement

the distribution of contrast agents

whether the lesion was significantly enlarged before and after CEUS combined with the characteristics in conventional ultrasound images has a certain diagnostic value.