Objective:

To study the ultrasonographic appearances and clinical features of invasive cribriform carcinoma (ICC) of breast for improving the understanding and diagnosis results of the disease.

Methods:

Twenty-one cases of ICC confirmed by pathol-ogy examination after surgery in International Peace Maternity and Child Health Hospital from Jan. 2008 to Aug. 2018 were collect-ed

and their ultrasonographic features and clinicopathological data were analyz

ed.

Results:

All patients were females. The age of onset was 33-78 years and the median age was 53 years old. All the lesions occurred unilaterally. 42.9% (9/21) cases had 100% sieve structure

23.8% (5/21) cases had 50%-99% sieve structure and 33.3% (7/21) cases had less than 50% sieve structure. Three cases combined with axillary lymph node metastasis. Ultrasonographic features: all lesions manifest as hypoechoic nodules. Combined with punctate calcification in 5 cases. About 90% lesions showed unclear boundaries and about 95% lesions showed irregular shapes. Blood flow signals could be detected internally and (or) peripherally in 71.4% lesions. Ultrasound diagnosis results: 95.2% (20/21) cases were diagnosed as breast imaging reporting and data system (BI-RADS) 4A or above

and 1 case was diagnosed as BI-RADS 3.

Conclusion:

By reviewing the ultrasonographic features and clinicopathological features of ICC

we could improve the understand-ing and diagnosis results of this disease.