To evaluate the value of histogram textural-analysis of PET/CT and multiparametric magnetic resonance imaging in the diagnosis of transition zone prostatic tumour.
Methods:
Thirty-six patients with transition zone prostatic tumour were enrolled in the study.
18
F-FDG PET/CT
T1WI
T2WI and DWI imag
es were available for histogram texture analysis. The differences of the image texture of tumour and non-tumour transition zone were analyzed by t test or Mann-Whitney U test. Diagnostic accuracy was assessed by the analysis of area under curve (AUC) of receiver operating characteristic (ROC) curve.
Results:
The mean of PET/CT and DWI
the skewness of T1WI were significantly higher in tumour (167.517.1
76.818.3
0.1660.447
respectively) than in non-tumour transition zone (115.315.8
54.610.8
-0.1880.433
respectively) (all
P
<0.05). Combining these parameters
AUC was 0.992 (95% CI: 0.972-1.000) with 100.0% sensitivity and 93.7% specificity.
Conclusion:
Texture-based detection of transition zone prostatic tumour is feasible on PET/CT and multiparametric MRI.