Objective:

To evaluate the value of texture analysis derived from T2WI in differential diagnosis between nasopharyngeal carcinoma (NPC) and nasopharyngeal hyperplasia (NPH).

Methods:

Forty-eight cases of NPC and NPH confirmed by operation and pathology were analyzed retrospectively. All of them were examined by magnetic resonance im

aging (MRI). Thirty cases were NPC and 18 cases were NPH. Two groups of lesions were analyzed by MaZda software. A total of groups of parameters were obtained by selecting the largest layer of the lesion on the T2WI image and measuring the parameters of the region of interest (ROI). Finally

multi-parameter combination were used to identify NPC and NPH.

Results:

The seven parameters of S(0

5) Entropy

S(5

5) Entropy

S(5

-5) Entropy

45dgr_RLNonUni

135dr_RLNonUni

GrSkewness and WavEnLH_s-3 were of statistical significance between the two groups (

P

＜0.05)

among which

the area under curve (AUC) of 135dr_RLNonUni

GrSkewness and WavEnLH_s-3 were 0.759

0.803 and 0.731

respectively

and the diagnostic accuracy was at a moderate level. In addition

the two- parameter combined analysis of this study found that the diagnostic efficacy of 135dr_RLNonUni + GrSkewness and GrSkewness + WavEnLH_s-3 in the identification of two groups of lesions were 0.824 and 0.833

respectively

and contrast to the single parameter

the accuracy of combined analysis of two parameters was better.

Conclusion:

Texture analysis of T2WI can be used to identify NPC and NPH.