Objective:

To explore diagnostic value of contrast-enhanced spectral mammography (CESM) in the detection and differentiation of breast lesions.

Methods:

The study included 151 patients with 157 breast lesions. After the lesions were observed on low energy (LE)

CESM and magnetic resonance imaging (MRI) images

Receiver operating characteristic (ROC) curves were compared

and calcul

ate the sensitivity

specificity and accuracy. According to the density of the affected breast

it can be divided into dense breast and non-dense breast.

Results:

The LE detected 134 lesions in 128 patients

including 39 invasive

3 non-invasive

and 92 benign. With CESM

154 lesions in 148 patients were detected

including 44 malignant lesions and 110 benign lesions. The area under curve (AUC) of CESM and LE was 0.97 and 0.89 (

P

＜0.05). In dense breast group

the AUC of CESM and LE were 0.97 and 0.87 (

P

＜0.05). The AUC of LE

CESM and MRI were 0.90

0.97 and 0.98

respectively

(

P

＞0.05).

Conclusion:

CESM is superior to LE in detection and diagnosis of lesions

and there is no significant difference between CESM and MRI. CESM has a better perfor-mance in dense breast.