The mortality of lung cancer is high all over the world

and it is increasing in China by years. Lung cancer puts tremendous threat on our survival and health. Lung cancer is characteristic of insidious onset and currently it is impossible to make a diagnosis of early-stage lung cancer with any effective and systematic methods. Thus

it is urgent to explore some novel ways to deal with this disease. Low-dose CT (LDCT) gets more and more attention because it plays a same role as effective as usual CT in identifying tiny lung lesions and the radiation dose is two thirds lower than the usual. Many accomplished and ongoing clinical trials get numerous data and results but still some similar problems exist in these trials

such as how to further improve the diagnostic efficiency

how to reduce the radiation dose

how to improve the cost-effectiveness et al. Only with these problems settled well can LDCT become the powerful weapon on lung cancer screening.