剪切波弹性成像联合超微血管显像对乳腺病灶良恶性的鉴别诊断价值

吕景; 张娜; 邸海燕; 杨震; 刘巍; 白芳芳

doi:10.19732/j.cnki.2096-6210.2020.05.005

您当前的位置：

首页 >

文章列表页 >

剪切波弹性成像联合超微血管显像对乳腺病灶良恶性的鉴别诊断价值

论著 | 更新时间：2025-12-15

- 剪切波弹性成像联合超微血管显像对乳腺病灶良恶性的鉴别诊断价值
- Value of shear wave elastography combined with super microvascular imaging in differential diagnosis of benign and malignant breast lesions
- 肿瘤影像学 2020年29卷第5期页码：448-452
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.19732/j.cnki.2096-6210.2020.05.005
  中图分类号：
- 网络出版：2020-10-28，
  
  纸质出版：2020-10-28
- 稿件说明：
移动端阅览
吕景,张娜,邸海燕,等. 剪切波弹性成像联合超微血管显像对乳腺病灶良恶性的鉴别诊断价值[J]. 肿瘤影像学, 2020, 29(5): 448-452 https://doi.

org/10.19732/j.cnki.2096-6210.2020.05.005
吕景,张娜,邸海燕,等. 剪切波弹性成像联合超微血管显像对乳腺病灶良恶性的鉴别诊断价值[J]. 肿瘤影像学, 2020, 29(5): 448-452 https://doi. DOI： 10.19732/j.cnki.2096-6210.2020.05.005.

org/10.19732/j.cnki.2096-6210.2020.05.005 DOI：

摘要

目的：

探讨剪切波弹性成像（shear wave elastography，SWE）联合超微血管显像（super microvascular imaging， SMI）在乳腺病灶良恶性鉴别诊断中的应用价值。

方法：

对236例乳腺占位性病变患者共272个病灶进行SWE及SMI检查。以手术后病理学检查结果为金标准，评价SWE、SMI及两者联合对乳腺病灶良恶性的鉴别诊断效能，并应用受试者工作特征（receiver operating characteristic，ROC）曲线分析SWE的最大值（E

max

）、平均值（E

mean

）、最小值（E min ）、标准差（SD）以及病灶与周边正常组织比值（E ratio ）对乳腺病灶良恶性的鉴别诊断价值。

结果：

272个病灶中，良性病灶125个，恶性病灶147个。恶性病灶的E

max

［（124.852.6）kPa

（26.515.4）kPa］、E

mean

［（70.533.6）kPa

（16.712.4）kPa］、E

min

［（27.316.2）kPa

（9.15.8）kPa］、SD［（24.713.5）kPa

（3.42.0）kPa］及E

ratio

（5.72.2

1.40.5）明显高于良性病灶（

＜0.01）。恶性病灶Alder血流分级Ⅱ～Ⅲ级者明显多于良性病灶（

＜0.01）。SWE联合SMI鉴别诊断乳腺病灶良恶性的灵敏度、特异度及准确率分别为97.3%、94.4%、96.0%。E

max

、E

mean

、E

min

、SD及E

ratio

鉴别诊断乳腺病灶良恶性的曲线下面积（area under curve，AUC）分别为0.938、0.882、0.806、0.870、0.904，当E

max

取76.8 kPa时，其鉴别诊断乳腺病灶良恶性的灵敏度和特异度最好，分别为93.5%和91.8%。

结论：

max

对乳腺病灶良恶性鉴别诊断具有较高的价值，SWE联合SMI有助于提高乳腺病灶良恶性鉴别诊断的准确率。

Abstract

Objective:

To investigate the application value of shear wave elastography (SWE) combined with superb microvascular imaging (SMI) in differential diagnosis of benign and malignant breast lesions.

Methods:

SWE and SMI examinations were performed on 272 lesions in 236 patients with breast lesions. The diagnostic efficacy of SWE

SMI and their combination in differentiating benign from malignant breast lesions were evaluated based on the results of surgical pathology. The value of the maximum (E

max

)

average (E

mean

)

minimum (E

min

)

standard deviation (SD) of SWE and the ratio of lesions to peripheral normal tissues (E

ratio

) in the differential diagnosis of benign and malignant breast lesions was analyzed by receiver operating characteristic (ROC) curve.

Results:

Among the 272 lesions

125 were benign and 147 were malignant. E

max

［(124.852.6) kPa

(26.5 15.4) kPa］

mean

［(70.533.6) kPa

(16.712.4) kPa］

min

［(27.316.2) kPa

(9.15.8) kPa］

SD［(24.713.5) kPa

(3.42.0) kPa］ and E

ratio

(5.72.2

1.40.5) in malignant lesions were significantly higher than those in benign lesions (

＜0.01). There were more cases of the Alder blood flow Ⅱ-Ⅲ grade in malignant lesions than that in benign lesions (

＜0.01). The sensitivity

specificity and accuracy of SWE combined with SMI in differentiating benign and malignant breast lesions were 97.3%

94.4% and 96.0%

respectively. The area under curve (AUC) of E

max

mean

min

SD and E

ratio

in differentiating benign and malignant breast lesions were 0.938

0.882

0.806

0.870 and 0.904

respectively. When E

max

was 76.8 kPa

the sensitivity and specificity of differentiating benign from malignant breast lesions were 93.5% and 91.8%

respectively.

Conclusion:

max

has highervalue in differential diagnosis of benign and malignant breast lesions

and SWE combined with SMI can improve the accuracy of differential diagnosis.

关键词

Keywords

references

浏览量

1227

下载量

CNKI被引量

文章被引用时，请邮件提醒。

提交

工具集

关联资源

超声造影在乳腺良恶性肿瘤鉴别诊断中的应用

剪切波弹性成像在评估儿童肾小球疾病中的应用价值

超微血流成像技术在乳腺BI-RADS 4类结节鉴别诊断中的应用及效能分析

常规MRI对交界性卵巢肿瘤的诊断价值

儿童肋骨软骨黏液样纤维瘤1例