Objective:

To investigate the differential features between intrahepatic cholangiocarcinoma (ICC) and hepatic inflammatory pseudotumor (IPT) by contrast-enhanced ultrasound (CEUS).

Methods:

The serum tumor maker

conventional ultrasound and CEUS images of 50 ICC lesions and 45 IPT lesions were analyzed

and the the differential diagnostic features of them were discussed.

Results:

There were significant differences in the increase o

f carbohydrate antigen 19-9 (CA19-9) between the two groups (

P

＜0.05). The conventional ultrasound features

including homogeneity of internal echo

blood flow signal and biliary dilatation

were statistically significant between the two groups (

P

＜0.05). Enhanced contrast dynamic mode

rapid hyperenhancement in the arterial phase and rapid wash out was significant differences between the two groups (

P

＜0.05). There were three modes of enhancement in the arterial phase of lesions: peripheral ring enhancement

global heterogeneous enhancement and global homogeneous enhancement

and the difference in enhancement modes between the two groups was statistically significant (

P

＜0.05).

Conclusion:

CEUS can provide more information for differential diagnosis of ICC and IPT lesions

which has certain diagnostic value.