To retrospectively analyze the guiding value of functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) in functional glioma surgery.
Methods:
The clinical data of 50 patients
with functional glioma who underwent surgical treatment in Shenzhen Longhua Peoples Hospital from January 2018 to January 2019 were collected for retrospective analysis
and the DTI
fMRI examination results and surgical results of the patients were collected.
Results:
The fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of high-grade gliomas were different from those of low-grade gliomas (
t=
9.128
8.535
P
<0.05). The incidence of fiber bundle destruction in high-grade gliomas was significantly higher than that of low-grade gliomas gliomas (
2
=4.393
P
<0.05)
and the fiber bundle displacement rate was significantly lower than that of low-grade glioma (
2
=4.462
P
<0.05). 41 patients (82.00%) had complete resection of tumor lesions. The complete resection rate and survival rate of patients with high-grade glioma were significantly lower than that of low-grade glioma (
2
=5.378
P
<0.05)
and the recurrence rate was higher than that of low-grade glioma (
2
=4.303
P
<0.05). The quality of life scores of patients with different grades of glioma after surgery were significantly higher than those before surgery
and the quality of life scores of patients with low-grade gliomas were higher than those of high-grade gliomas (
t
=10.812
15.224
19.485
P
<0.05).
Conclusion:
Preoperative fMRI combined with DTI technology for grading functional gliomas is of great significance for improving the complete resection rate of tumor lesions and reducing the mortality and recurrence rate.