Objective:

To analyze the value of contrast-enhanced ultrasound in the diagnosis of breast cancer in souther

n Xinjiang plateau and plain areas.

Methods:

A total of 100 suspected breast cancer patients in Second People's Hospital of Kashi Prefecture from September 2018 to April 2021 were selected as the research objects. According to different regions

patients were divided into 50 cases in the experimental group (highland area) and 50 cases in the control group (plain area). The characteristic parameters of ultrasound images of patients were collected. Pathological diagnosis was used as the gold standard in the group

and the accuracies of ultrasound images in diagnosis of breast cancer in different regions were compared; the parameters of contrast-enhanced ultrasoundin diagnosis of breast cancer in different regions were also compared; receiver operating characteristic (ROC) curves were used to analyze the diagnostic efficiency of parameters with statistically significant differences.

Results:

Taking pathological examination as the gold standard

the accuracy of ultrasound in diagnosis of the experimental group was 83.87% (26/31)

and accuracy of the control group was 88.87% (29/33)

the difference was not statistically significant (

P

＞0.05). There was no significant difference in peak time

average transit time

and local blood flow (

P

0.05). The peak intensity

elastography score and local blood volume of the experimental group were significantly higher than those of the control group (

P

＜0.05); The best cut-off values of the peak intensity

elastography score and local blood volume in diagnosis of breast cancer in southern Xinjiang plateau were 45.52%

3.93 points

2 170.15 mL

and area under curve (AUC) values were 0.694

0.733

and 0.812

respectively; ROC curve analysis showed that peak intensity

elastography score

and local blood in experimental group were higher than those in control group. The best cut-off values of capacity in the diagnosis of breast cancer in plain areas were 35.25%

4.36 points

1 619.40 mL; AUC values were 0.738

0.818

and 0.879

respectively.

Conclusion:

Contrast-enhanced ultrasound in the diagnosis of breast cancer patients in both southern Xinjiang plateau and plain areas has good diagnostic reference value

but there are differences in parameters such as peak intensity

elastography score

and local blood volume. Clinicians use ultrasound images for breast cancer. In the analysis of nodules

regional factors need to be considered.