Objective:

To analyze the imaging features of primary breast diffuse large B cell lymphoma (PB-DLBCL) on magnetic resonance imaging (MRI) and to improve the understanding of this disease.

Methods:

Three PB-DLBCL patients were included in this study. All the patients were pathologically confirmed and were with complete MRI images. The findings

and features of MRI images were retrospectively analyzed.

Results:

There were 3 females (six lesions) aged 47-66 years old

with a mean age of 55.679.61 years. All lesions were located on the ipsilateral side: one case in the left breast

two cases in the right breast. Most lesions demonstrated clear boundaries (4/6) without burrs on edges (6/6)

isointense (3/6) or hypointense (3/6) on T1-weighted imaging (T1WI)

hyperintense on T2-weighted imaging (T2WI) fat suppression sequences and sharply hyperintense on diffusion- weighted imaging (DWI). The apparent diffusion coefficient (ADC) values was (0.37-0.79)10

-3

mm

2

/s. Dynamic contrast enhanced MRI images showed early homogeneous enhancement of the lesions with penetrating vessels

hyperintense linear enhancement and peripheral enhancement on the delayed images. The time-signal intensity curves (TIC) were plateau type or washout type.

Conclusion:

PB-DLBCL has some MRI features

and DWI is of great help in its differential diagnosis.