将数字乳腺体层合成(digital breast tomosynthesis,DBT)对乳腺癌的诊断效能分别与磁共振成像(magnetic resonance imaging,MRI)及全视野数字乳腺X线摄影(full-field digital mammography,FFDM)进行比较,探讨DBT对乳腺癌诊断的临床价值。
方法:
选取在复旦大学附属肿瘤医院、上海交通大学医学院附属瑞金医院及北京大学第一医院3家中心入组的196例患者进行乳腺FFDM和DBT检查,同时进行MRI扫描。根据乳腺影像报告和数据系统(Breast Imaging Reporting and Data System,BI-RADS)对FFDM、DBT、MRI的可疑征象进行分类,将病理学检查结果或临床诊断结果作为最终诊断结果,计算各类影像学检查结果与最终诊断结果的一致性,统计DBT和FFDM、MRI与最终诊断结果一致性的差异,评价DBT技术对乳腺癌的诊断效能;对FFDM和DBT检查进行偏好性评价,评价包含病灶可见性、病灶边缘清晰程度、良恶性鉴别能力、总体评估4个方面,评价FFDM和DBT对病灶显示的差异。
To evaluate the clinical value of digital breast tomosynthesis (DBT) in breast cancer diagnosis and the diagnostic efficacy in breast cancer of DBT was compared with magnetic resonance imaging (MRI) and full-field mammography (FFDM).
Methods:
A total of 196 patients from Fudan University Shanghai Cancer Center
Shanghai Jiao T
ong University School of Medicine Ruijin Hospital
Peking University First Hospital were selected for FFDM
DBT
and MRI scanning. According to the Breast Imaging Reporting and Data System (BI-RADS) classification of lesions detected by FFDM
DBT and MRI
pathological results or clinical diagnosis were taken as the final diagnosis results to calculate the consistency of each image type and the final diagnosis results. The differences between each-type consistency were counted to evaluate the diagnostic efficacy of DBT technology in breast cancer. The bias evaluation of FFDM and DBT images was evaluated
including lesion visibility
lesion edge clarity
benign malignant resolution ability
and overall evaluation
to evaluate the difference between FFDM and DBT in lesion display.
Results:
The sensitivity and accuracy of DBT in breast cancer diagnosis were significantly better than FFDM. For the display of different types of lesions
DBT had a significant bias compared with FFDM. The DBT display quality of lesions was better. Although MRI was slightly better than DBT in the sensitivity
specificity and accuracy of breast cancer diagnosis
there is no statistically significant difference.
Conclusion:
The diagnostic efficacy of DBT in breast cancer is superior to FFDM and close to MRI. DBT displayed lesions better than FFDM.